Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1. - Wikidata - wikimedia - TriplyDB

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

http://www.wikidata.org/entity/Q35210750

about

The role of proopiomelanocortin (POMC) neurones in feeding behaviour Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors ARNT2 mutation causes hypopituitarism, post-natal microcephaly, visual and renal anomalies Postnatal Sim1 deficiency causes hyperphagic obesity and reduced Mc4r and oxytocin expression Oxytocin deficiency mediates hyperphagic obesity of Sim1 haploinsufficient mice Oxytocin: the great facilitator of life.Separate necdin domains bind ARNT2 and HIF1alpha and repress transcription The Role of the Neuroprotective Factor Npas4 in Cerebral Ischemia Obesity genetics in mouse and human: back and forth, and back again Contribution of genoarchitecture to understanding forebrain evolution and development, with particular emphasis on the amygdala Embryonic development of the hypothalamic feeding circuitry: Transcriptional, nutritional, and hormonal influences The Role of PVH Circuits in Leptin Action and Energy Balance Small 6q16.1 Deletions Encompassing POU3F2 Cause Susceptibility to Obesity and Variable Developmental Delay with Intellectual Disability Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene Cloning and functional analysis of hypothalamic homeobox gene Bsx1a and its isoform, Bsx1b Expression of Arnt and Arnt2 mRNA in developing murine tissues NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants The non-evaginated secondary prosencephalon of vertebrates A treasure trove of hypothalamic neurocircuitries governing body weight homeostasis Control of food intake and energy expenditure by Nos1 neurons of the paraventricular hypothalamus.Role of developmental factors in hypothalamic function Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area.Roles for gamma-aminobutyric acid in the development of the paraventricular nucleus of the hypothalamus Neuronal remodeling during metamorphosis is regulated by the alan shepard (shep) gene in Drosophila melanogaster.Inferring Selective Constraint from Population Genomic Data Suggests Recent Regulatory Turnover in the Human Brain.Differential regulation of the zebrafish orthopedia 1 gene during fate determination of diencephalic neurons.Mapping peptidergic cells in Drosophila: where DIMM fits in.Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus.Genetic analysis of single-minded 1 gene in early-onset severely obese children and adolescents Inducible neuronal inactivation of Sim1 in adult mice causes hyperphagic obesity.Genome-wide survey and expression analysis of the bHLH-PAS genes in the amphioxus Branchiostoma floridae reveal both conserved and diverged expression patterns between cephalochordates and vertebrates A genomic atlas of mouse hypothalamic development.Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture Different transcriptional properties of mSim-1 and mSim-2.Sim1 is a novel regulator in the differentiation of mouse dorsal raphe serotonergic neurons.Abnormal Paraventricular Nucleus of Hypothalamus and Growth Retardation Associated with Loss of Nuclear Receptor Gene COUP-TFII Gene regulation in the magnocellular hypothalamo-neurohypophysial system.Leptin and the control of body weight: a review of its diverse central targets, signaling mechanisms, and role in the pathogenesis of obesity.Interstitial Deletions at 6q14.1-q15 Associated with Obesity, Developmental Delay and a Distinct Clinical Phenotype.

P2860

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P2860

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

http://www.wikidata.org/entity/Q35210750

description

1998 nî lūn-bûn

@nan

1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@ast

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@en

type

label

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@ast

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@en

prefLabel

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@ast

Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@en

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Genes & Development

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Development of neuroendocrine lineages requires the bHLH-PAS transcription factor SIM1.

@en

P2093

C M Fan

http://www.w3.org/2001/XMLSchema#string

J L Michaud

http://www.w3.org/2001/XMLSchema#string

N R May

http://www.w3.org/2001/XMLSchema#string

T Rosenquist

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P2860

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome

Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

Positional cloning of the mouse circadian clock gene

DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins

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3264-3275

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10.1101/GAD.12.20.3264

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20

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12

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1998-10-01T00:00:00Z

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9784500

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317216

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