The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein
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The mechanism of release of P-TEFb and HEXIM1 from the 7SK snRNP by viral and cellular activators includes a conformational change in 7SKMice transgenic for equine cyclin T1 and ELR1 are susceptible to equine infectious anemia virus infectionInhibition of Tat activity by the HEXIM1 proteinTat-SF1 protein associates with RAP30 and human SPT5 proteinsTRIM5α and Species Tropism of HIV/SIVAcetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cellsThe human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionThe structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylationAnalysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription.Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequencesPhosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongationInteraction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasomeCDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNARelief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoterDomains in the SPT5 protein that modulate its transcriptional regulatory propertiesThe growth factor granulin interacts with cyclin T1 and modulates P-TEFb-dependent transcriptionTranscriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent mannerCoordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcriptionBinding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitorTIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcriptionCrystal structure of HIV-1 Tat complexed with human P-TEFbRole of Zn2+ ions in host-virus interactionsRecruitment of human cyclin T1 to nuclear bodies through direct interaction with the PML proteinMAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent mannerDevelopmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcriptionSIRT1 regulates HIV transcription via Tat deacetylationA new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongationTat gets the "green" light on transcription initiationTranscriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a cureCyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV TatStructural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAVThe structure of CDK4/cyclin D3 has implications for models of CDK activationAFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoterTat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcriptionCyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcriptionRequirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcriptionTFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcriptionThree RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences
P2860
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P2860
The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein
description
1998 nî lūn-bûn
@nan
1998 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@ast
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@en
type
label
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@ast
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@en
prefLabel
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@ast
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@en
P2093
P2860
P356
P1433
P1476
The interaction between HIV-1 ...... ed in the murine CycT1 protein
@en
P2093
C H Herrmann
D R Littman
M E Garber
T P Mayall
V N KewalRamani
P2860
P304
P356
10.1101/GAD.12.22.3512
P577
1998-11-01T00:00:00Z