A pilot study of subcutaneous decitabine in β-thalassemia intermedia - Wikidata - wikimedia - TriplyDB

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

http://www.wikidata.org/entity/Q35212344

about

Epigenetic regulation of fetal globin gene expression in adult erythroid cells Trials with 'epigenetic' drugs: an update Advancements in the delivery of epigenetic drugs Clinical development of demethylating agents in hematology Evaluation of noncytotoxic DNMT1-depleting therapy in patients with myelodysplastic syndromes.Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies Non-transfusion-dependent thalassemias.A randomized phase I/II trial of HQK-1001, an oral fetal globin gene inducer, in β-thalassaemia intermedia and HbE/β-thalassaemia.Alternative options for DNA-based experimental therapy of β-thalassemia.Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.Evaluation of Signaling Pathways Involved in γ-Globin Gene Induction Using Fetal Hemoglobin Inducer Drugs.Evaluation of Novel Fetal Hemoglobin Inducer Drugs in Treatment of β-Hemoglobinopathy Disorders.Management of non-transfusion-dependent thalassemia: a practical guide.A complicated disease: what can be done to manage thalassemia major more effectively?Fetal hemoglobin regulation in β-thalassemia: heterogeneity, modifiers and therapeutic approaches.Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.Combining gene therapy and fetal hemoglobin induction for treatment of β-thalassemia.Current Standards of Care and Long Term Outcomes for Thalassemia and Sickle Cell Disease.Thalidomide has a significant effect in patients with thalassemia intermedia.Orphan Drugs and Potential Novel Approaches for Therapies of β-Thalassemia: Current Status and Future Expectations Erythropoiesis: insights into pathophysiology and treatments in 2017.Hydroxyurea Treated β-Thalassemia Children Demonstrate a Shift in Metabolism Towards Healthy Pattern Fetal Hemoglobin Induction by Epigenetic Drugs

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P2860

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

http://www.wikidata.org/entity/Q35212344

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@ast

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@en

type

label

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@ast

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@en

prefLabel

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@ast

A pilot study of subcutaneous decitabine in β-thalassemia intermedia

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BLOOD-2011-03-341909

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A pilot study of subcutaneous decitabine in β-thalassemia intermedia

@en

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Felicia L Trachtenberg

http://www.w3.org/2001/XMLSchema#string

Frans A Kuypers

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Hae-Young Kim

http://www.w3.org/2001/XMLSchema#string

Janet Kwiatkowski

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Nancy F Olivieri

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Russell E Ware

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Vivek Thayalasuthan

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Yogen Saunthararajah

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P2860

The inherited diseases of hemoglobin are an emerging global health burden.

Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

A simple assay for frequency of chromosome breaks and loss (micronuclei) by flow cytometry of human reticulocytes.

Intrinsic and extrinsic control of hemopoietic stem cell numbers: mapping of a stem cell gene

Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia

Platelet count and the risk for thrombosis and death in the elderly.

In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine.

Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

Cellular differentiation, cytidine analogs and DNA methylation.

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2708-2711

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scholarly article

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10.1182/BLOOD-2011-03-341909

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10

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118

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Elliott Vichinsky

Thalassemia Clinical Research Network

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2011-06-23T00:00:00Z

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51245590

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21700776

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3172790

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