Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair - Wikidata - wikimedia - TriplyDB

Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair

Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair

http://www.wikidata.org/entity/Q35213388

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Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease The maintenance of mitochondrial DNA integrity--critical analysis and update Repair of oxidative DNA damage and cancer: recent progress in DNA base excision repair Mitochondrial DNA damage and its consequences for mitochondrial gene expression Repair of persistent strand breaks in the mitochondrial genome Mitochondrial DNA damage induced autophagy, cell death, and disease Genetic instability in budding and fission yeast-sources and mechanisms Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism Inhibition of hydrogen sulfide biosynthesis sensitizes lung adenocarcinoma to chemotherapeutic drugs by inhibiting mitochondrial DNA repair and suppressing cellular bioenergetics.Selective mitochondrial DNA degradation following double-strand breaks A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease.DNA damage related crosstalk between the nucleus and mitochondria.Mitochondrial genome maintenance in health and disease.Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus Regulation of mitochondrial poly(ADP-Ribose) polymerase activation by the β-adrenoceptor/cAMP/protein kinase A axis during oxidative stress.Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels.Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro.Mitochondria, energetics, epigenetics, and cellular responses to stress.Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.CHK2 kinase in the DNA damage response and beyond Deficiency in repair of the mitochondrial genome sensitizes proliferating myoblasts to oxidative damage Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans.In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans.Suppression of oxidative phosphorylation in mouse embryonic fibroblast cells deficient in apurinic/apyrimidinic endonuclease.Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE.Persistent damage induces mitochondrial DNA degradation.Mitochondria as a target of environmental toxicants.Mitochondrial DNA damage induces apoptosis in senescent cells Exonuclease of human DNA polymerase gamma disengages its strand displacement function.Mitochondrial-associated metabolic disorders: foundations, pathologies and recent progress.Oxidants and not alkylating agents induce rapid mtDNA loss and mitochondrial dysfunction.Effects on DNA Damage and/or Repair Processes as Biological Mechanisms Linking Psychological Stress to Cancer Risk Mitochondrial DNA maintenance: an appraisal.Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells Mitochondrial poly(ADP-ribose) polymerase: The Wizard of Oz at work.

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Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repair

http://www.wikidata.org/entity/Q35213388

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Apoptosis induced by persisten ...... /endonuclease) in their repair

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Apoptosis induced by persisten ...... /endonuclease) in their repair

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Apoptosis induced by persisten ...... /endonuclease) in their repair

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Apoptosis induced by persisten ...... /endonuclease) in their repair

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JBC.M110.215715

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Journal of Biological Chemistry

P1476

Apoptosis induced by persisten ...... /endonuclease) in their repair

@en

P2093

Anne W Tann

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Bartosz Szczesny

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Bennett Van Houten

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Gregor Meiss

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Istvan Boldogh

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Sankar Mitra

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Wei Qian

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P2860

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties

Biochemical analysis of human Dna2

Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

The DNA-damage response in human biology and disease

Is the oxidative stress theory of aging dead?

NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

Sequence and organization of the human mitochondrial genome

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31975-31983

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scholarly article

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10.1074/JBC.M110.215715

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37

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286

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2011-07-18T00:00:00Z

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21768646

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apoptotic process

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3173182

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