Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates
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Caught in the Act: The 1.5 Å Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate †Structure of HIV-1 protease in complex with potent inhibitor KNI-272 determined by high-resolution X-ray and neutron crystallographyCatalytic Water Co-Existing with a Product Peptide in the Active Site of HIV-1 Protease Revealed by X-Ray Structure AnalysisProtein conformational dynamics in the mechanism of HIV-1 protease catalysisUsing the experimentally determined components of the overall rotational diffusion tensor to restrain molecular shape and size in NMR structure determination of globular proteins and protein-protein complexes.Direct use of 15N relaxation rates as experimental restraints on molecular shape and orientation for docking of protein-protein complexes.Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.Linkers in the structural biology of protein-protein interactionsShort Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons.Isotopic fractionation in proteins as a measure of hydrogen bond length.Placevent: an algorithm for prediction of explicit solvent atom distribution-application to HIV-1 protease and F-ATP synthase.A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad.
P2860
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P2860
Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates
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2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@ast
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@en
type
label
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@ast
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@en
prefLabel
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@ast
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@en
P2093
P2860
P356
P1476
Crystal structure of HIV-1 pro ...... d between catalytic aspartates
@en
P2093
J-L Ferrer
Smita Mahale
Vishal Prashar
P2860
P304
18464-18469
P356
10.1073/PNAS.0605809103
P407
P577
2006-11-20T00:00:00Z