Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
about
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretaseVascular aspects of cognitive impairment and dementiaThe pathobiology of vascular dementiaHypertension: a harbinger of stroke and dementiaImpaired Aβ clearance: a potential link between atherosclerosis and Alzheimer's diseaseDeficiency of the copper chaperone for superoxide dismutase increases amyloid-β productionDepletion of GGA1 and GGA3 mediates postinjury elevation of BACE1The normal and pathologic roles of the Alzheimer's β-secretase, BACE1Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersDose-specific effect of simvastatin on hypoxia-induced HIF-1α and BACE expression in Alzheimer's disease cybrid cells.The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing miceIntact memory in TGF-β1 transgenic mice featuring chronic cerebrovascular deficit: recovery with pioglitazoneInhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology.Biological changes associated with healthy versus pathological aging: a symposium review.Elevated Aβ42 in aged, non-demented individuals with cerebral atherosclerosis.Viable mouse gene ablations that robustly alter brain Aβ levels are rare.Alterations in the red blood cell membrane proteome in alzheimer's subjects reflect disease-related changes and provide insight into altered cell morphologyAssociation between total-Tau and brain atrophy one year after first-ever stroke.Expression and Transcriptional Regulation of Human ATP6V1A Gene in Gastric Cancers.RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environmentEvidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.The neurovascular unit in brain function and disease.Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.Effect of aging on cellular mechanotransductionOligemic hypoperfusion differentially affects tau and amyloid-{beta}.Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.Forebrain-dominant deficit in cerebrovascular reactivity in Alzheimer's disease.Optical imaging in an Alzheimer's mouse model reveals amyloid-β-dependent vascular impairment.Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's diseasePhosphodiesterase III inhibitor promotes drainage of cerebrovascular β-amyloidTransgenic mice overexpressing APP and transforming growth factor-beta1 feature cognitive and vascular hallmarks of Alzheimer's diseaseNew therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy.Mutant amyloid precursor protein differentially alters adipose biology under obesogenic and non-obesogenic conditions.The overlap between neurodegenerative and vascular factors in the pathogenesis of dementiaBlood pressure and dementia - a comprehensive review.Two novel DNA motifs are essential for BACE1 gene transcriptionTimosaponin-BII inhibits the up-regulation of BACE1 induced by ferric chloride in rat retinaCD36 upregulation mediated by intranasal LV-NRF2 treatment mitigates hypoxia-induced progression of Alzheimer's-like pathogenesis.
P2860
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P2860
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@ast
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@en
type
label
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@ast
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@en
prefLabel
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@ast
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@en
P2093
P2860
P50
P921
P356
P1476
Hypoxia facilitates Alzheimer' ...... gulating BACE1 gene expression
@en
P2093
Guiqiong He
L Eric Huang
Weihui Zhou
Xiulian Sun
P2860
P304
18727-18732
P356
10.1073/PNAS.0606298103
P407
P577
2006-11-22T00:00:00Z