Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.
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Silencing of OB-RGRP in mouse hypothalamic arcuate nucleus increases leptin receptor signaling and prevents diet-induced obesityLentiviral vectors in gene therapy: their current status and future potentialGeneration of diverse neural cell types through direct conversionProtective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based VaccineRNA Interference and Single Particle Tracking Analysis of Hepatitis C Virus EndocytosisGene therapy for hemophiliaQuantitative comparison of constitutive promoters in human ES cellsRetinal degeneration progression changes lentiviral vector cell targeting in the retinaHuman immunodeficiency virus type 1 Vpu and cellular TASK proteins suppress transcription of unintegrated HIV-1 DNA.Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine.Molecular engineering of viral gene delivery vehiclesA novel and efficient gene transfer strategy reduces glial reactivity and improves neuronal survival and axonal growth in vitro.Nonintegrating lentiviral vectors can effectively deliver ovalbumin antigen for induction of antitumor immunity.Long-term episomal transgene expression from mitotically stable integration-deficient lentiviral vectors.Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene EditingPuromycin-resistant lentiviral control shRNA vector, pLKO.1 induces unexpected cellular differentiation of P19 embryonic stem cells.Hybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.Gene therapy for monogenic liver diseases: clinical successes, current challenges and future prospects.Transgenic expression of human glial cell line-derived neurotrophic factor from integration-deficient lentiviral vectors is neuroprotective in a rodent model of Parkinson's disease.Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity.LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectivesA nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malariaImmunization delivered by lentiviral vectors for cancer and infectious diseases.Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproductionNotable reduction in illegitimate integration mediated by a PPT-deleted, nonintegrating lentiviral vector.Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant.Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic riskThe role of unintegrated DNA in HIV infectionHepatitis C virus stimulates the phosphatidylinositol 4-kinase III alpha-dependent phosphatidylinositol 4-phosphate production that is essential for its replication.Development of viral vectors for use in cardiovascular gene therapy.MuLV IN mutants responsive to HDAC inhibitors enhance transcription from unintegrated retroviral DNA.Therapeutic Vaccine Strategies against Human Papillomavirus.Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors.Methods for gene transfer to the central nervous system.Transient Expression of Green Fluorescent Protein in Integrase-Defective Lentiviral Vector-Transduced 293T Cell Line.Use of a Novel Integrase-Deficient Lentivirus for Targeted Anti-Cancer Therapy With Survivin Promoter-Driven Diphtheria Toxin AIntegrase-deficient lentiviral vectors mediate efficient gene transfer to human vascular smooth muscle cells with minimal genotoxic risk.Human macrophages support persistent transcription from unintegrated HIV-1 DNA.Selective killing of HIV-1-positive macrophages and T cells by the Rev-dependent lentivirus carrying anthrolysin O from Bacillus anthracis.Gene therapy for the prevention of vein graft disease
P2860
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P2860
Lentiviral vectors with a defective integrase allow efficient and sustained transgene expression in vitro and in vivo.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@ast
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@en
type
label
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@ast
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@en
prefLabel
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@ast
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@en
P2093
P2860
P356
P1476
Lentiviral vectors with a defe ...... pression in vitro and in vivo.
@en
P2093
Caroline Petit
Chamsy Sarkis
Charline Ladroue
Che Serguera
Hamid Mammeri
Jacques Mallet
Martine Barkats
Stéphanie Philippe
P2860
P304
17684-17689
P356
10.1073/PNAS.0606197103
P407
P577
2006-11-09T00:00:00Z