about
The Role and Potential Therapeutic Implications of the Fibroblast Growth Factors in Energy Balance and Type 2 Diabetes.Improved glucose metabolism in vitro and in vivo by an allosteric monoclonal antibody that increases insulin receptor binding affinityAn allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lep(ob) /Lep(ob) mouse.Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties.Selective allosteric antibodies to the insulin receptor for the treatment of hyperglycemic and hypoglycemic disorders.Theoretical and computational studies of peptides and receptors of the insulin family.A Novel Allosteric Insulin Receptor-Activating Antibody Reduces Hyperglycemia without Hypoglycemia in Diabetic Cynomolgus Monkeys.Acute Treatment With XMetA Activates Hepatic Insulin Receptors and Lowers Blood Glucose in Normal Mice.Inhibition of insulin receptor function by a human, allosteric monoclonal antibody: a potential new approach for the treatment of hyperinsulinemic hypoglycemia.XMetA, an allosteric monoclonal antibody to the insulin receptor, improves glycaemic control in mice with diet-induced obesity.Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Receptor antibodies as novel therapeutics for diabetes.
@ast
Receptor antibodies as novel therapeutics for diabetes.
@en
type
label
Receptor antibodies as novel therapeutics for diabetes.
@ast
Receptor antibodies as novel therapeutics for diabetes.
@en
prefLabel
Receptor antibodies as novel therapeutics for diabetes.
@ast
Receptor antibodies as novel therapeutics for diabetes.
@en
P2860
P1476
Receptor antibodies as novel therapeutics for diabetes.
@en
P2093
Sara G Vienberg
P2860
P304
P356
10.1126/SCITRANSLMED.3003447
P407
P577
2011-12-01T00:00:00Z