A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
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Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compoundsPrediction of chemical respiratory sensitizers using GARD, a novel in vitro assay based on a genomic biomarker signatureIn vitro methods for hazard assessment of industrial chemicals - opportunities and challengesIntegrated Computational Solution for Predicting Skin Sensitization Potential of MoleculesPredicting full thickness skin sensitization using a support vector machineAnchoring molecular mechanisms to the adverse outcome pathway for skin sensitization: Analysis of existing data.Predicting skin sensitizer potency based on in vitro data from KeratinoSens and kinetic peptide binding: global versus domain-based assessment.Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data.Transcriptional profiling of human dendritic cell populations and models--unique profiles of in vitro dendritic cells and implications on functionality and applicabilitySkin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.Evaluation of high throughput gene expression platforms using a genomic biomarker signature for prediction of skin sensitization.Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany.Non-animal test methods for predicting skin sensitization potentials.In vitro approaches for detection of chemical sensitization.Prediction of skin sensitizers using alternative methods to animal experimentation.Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.Reporter cell lines for skin sensitization testing.Testing Human Skin and Respiratory Sensitizers-What Is Good Enough?State of the art in non-animal approaches for skin sensitization testing: from individual test methods towards testing strategies.Contact dermatitis: in pursuit of sensitizer's molecular targets through proteomics.Discrimination of skin sensitizers from non-sensitizers by interleukin-1α and interleukin-6 production on cultured human keratinocytes.Silver Nanocoating Technology in the Prevention of Prosthetic Joint Infection.The involvement of the Toll-like receptor signaling and Nrf2-Keap1 pathways in the in vitro regulation of IL-8 and HMOX1 for skin sensitization.Genomic allergen rapid detection in-house validation--a proof of concept.Induction of skin sensitization is augmented in Nrf2-deficient mice.Respiratory sensitization: toxicological point of view on the available assays.Pattern rules: biomarker signatures for sensitization as an alternative to animal testing.
P2860
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P2860
A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A genomic biomarker signature ...... ro alternative to animal tests
@ast
A genomic biomarker signature ...... ro alternative to animal tests
@en
type
label
A genomic biomarker signature ...... ro alternative to animal tests
@ast
A genomic biomarker signature ...... ro alternative to animal tests
@en
prefLabel
A genomic biomarker signature ...... ro alternative to animal tests
@ast
A genomic biomarker signature ...... ro alternative to animal tests
@en
P2093
P2860
P356
P1433
P1476
A genomic biomarker signature ...... ro alternative to animal tests
@en
P2093
Ann-Sofie Albrekt
Carl A K Borrebaeck
Henrik Johansson
Malin Lindstedt
P2860
P356
10.1186/1471-2164-12-399
P407
P577
2011-08-08T00:00:00Z