Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
about
Spermatogonial stem cell autotransplantation and germline genomic editing: a future cure for spermatogenic failure and prevention of transmission of genomic diseasesExperimental methods to preserve male fertility and treat male factor infertilityNRG1 and KITL Signal Downstream of Retinoic Acid in the Germline to Support Soma-Free Syncytial Growth of Differentiating Spermatogonia.Delivery of Cas9 Protein into Mouse Zygotes through a Series of Electroporation Dramatically Increases the Efficiency of Model CreationIsolation and Identification of Prepubertal Buffalo (Bubalus bubalis) Spermatogonial Stem Cells.An Efficient Method for Generation of Transgenic Rats Avoiding Embryo ManipulationModeling Disease In Vivo With CRISPR/Cas9.Long Evans rat spermatogonial lines are effective germline vectors for transgenic rat production.Update of neurotrophic factors in neurobiology of addiction and future directions.Road to the future of systems biotechnology: CRISPR-Cas-mediated metabolic engineering for recombinant protein production.To CRISPR and beyond: the evolution of genome editing in stem cells.A Medium-Throughput Single Cell CRISPR-Cas9 Assay to Assess Gene Essentiality.A guide to designing germline-dependent epigenetic inheritance experiments in mammals.Xenopus laevis as a model system to study cytoskeletal dynamics during axon pathfinding.Leapfrogging: primordial germ cell transplantation permits recovery of CRISPR/Cas9-induced mutations in essential genesTransfer of a Mouse Artificial Chromosome into Spermatogonial Stem Cells Generates Transchromosomic Mice.Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9.Gene Editing in Rat Embryonic Stem Cells to Produce In Vitro Models and In Vivo Reporters.Discovering in vitro spermatogenesis stimulating factors.A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid.Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring.DDX4-EGFP transgenic rat model for the study of germline development and spermatogenesis.Rattus norvegicus Spermatogenesis Colony-Forming Assays.Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system.Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system.Biology and manipulation technologies of male germline stem cells in mammals
P2860
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P2860
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
description
2015 nî lūn-bûn
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
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2015 թվականի մարտին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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name
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@ast
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@en
type
label
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@ast
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@en
prefLabel
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@ast
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@en
P2093
P2860
P1433
P1476
Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells
@en
P2093
Alexandra E Waits
F Kent Hamra
Gerardo A Medrano
Jaideep Chaudhary
James M Hotaling
Karen M Chapman
Marcelo A Nobrega
Priscilla Jaichander
P2860
P304
P356
10.1016/J.CELREP.2015.02.040
P50
P577
2015-03-12T00:00:00Z