Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence.
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Eastern equine encephalitis virus in mice I: clinical course and outcome are dependent on route of exposureResidue 82 of the Chikungunya virus E2 attachment protein modulates viral dissemination and arthritis in miceRole of heparan sulfate in sexually transmitted infectionsLoss of Glycosaminoglycan Receptor Binding after Mosquito Cell Passage Reduces Chikungunya Virus InfectivitySelective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian CellsRespiratory insufficiency correlated strongly with mortality of rodents infected with West Nile virus.Bioluminescent imaging and histopathologic characterization of WEEV neuroinvasion in outbred CD-1 miceDeliberate attenuation of chikungunya virus by adaptation to heparan sulfate-dependent infectivity: a model for rational arboviral vaccine designRNA viruses can hijack vertebrate microRNAs to suppress innate immunity.Ability of the Encephalitic Arbovirus Semliki Forest Virus To Cross the Blood-Brain Barrier Is Determined by the Charge of the E2 GlycoproteinInterferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate.Identification of Functional Determinants in the Chikungunya Virus E2 Protein.Brugia malayi microfilariae transport alphaviruses across the mosquito midgutThe sweet spot: defining virus-sialic acid interactions.Natural variation in the heparan sulfate binding domain of the eastern equine encephalitis virus E2 glycoprotein alters interactions with cell surfaces and virulence in miceIn vivo imaging in an ABSL-3 regional biocontainment laboratory.A single-amino-acid polymorphism in Chikungunya virus E2 glycoprotein influences glycosaminoglycan utilization.Mutagenesis analysis of T380R mutation in the envelope protein of yellow fever virus.Genome-Wide Screening Uncovers the Significance of N-Sulfation of Heparan Sulfate as a Host Cell Factor for Chikungunya Virus Infection.Host translation shutoff mediated by non-structural protein 2 is a critical factor in the antiviral state resistance of Venezuelan equine encephalitis virus.Both RIG-I and MDA5 detect alphavirus replication in concentration-dependent mode.Stable, high-level expression of reporter proteins from improved alphavirus expression vectors to track replication and dissemination during encephalitic and arthritogenic disease.Alphaviruses suppress host immunity by preventing myeloid cell replication and antagonizing innate immune responses.Can understanding the virulence mechanisms of RNA viruses lead us to a vaccine against eastern equine encephalitis virus and other alphaviruses?Analysis of murine B-cell epitopes on Eastern equine encephalitis virus glycoprotein E2.Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models.Reconstruction of the cell entry pathway of an extinct virusThe genetics of alphavirusesEvolution of New Variants/Mutants of JE Virus, Its Effect on Neurovirulence, Antigenicity, Host Immune Responses and Disease Transmission in Endemic Areas
P2860
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P2860
Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@ast
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@en
type
label
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@ast
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@en
prefLabel
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@ast
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@en
P2093
P2860
P356
P1476
Heparan sulfate binding by nat ...... ruses promotes neurovirulence.
@en
P2093
Christina L Gardner
Kate D Ryman
William B Klimstra
P2860
P304
16026-16031
P356
10.1073/PNAS.1110617108
P407
P577
2011-09-06T00:00:00Z