Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy - Wikidata - wikimedia - TriplyDB

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

http://www.wikidata.org/entity/Q35233401

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The relationship between terminal functionalization and molecular weight of a gene delivery polymer and transfection efficacy in mammary epithelial 2-D cultures and 3-D organotypic cultures Uptake and transfection with polymeric nanoparticles are dependent on polymer end-group structure, but largely independent of nanoparticle physical and chemical properties.A novel assay for quantifying the number of plasmids encapsulated by polymer nanoparticles.Differential polymer structure tunes mechanism of cellular uptake and transfection routes of poly(β-amino ester) polyplexes in human breast cancer cells Poly(β-amino ester)-DNA complexes: time-resolved fluorescence and cellular transfection studies Mutant MCP-1 protein delivery from layer-by-layer coatings on orthopedic implants to modulate inflammatory response.Discovery of cationic polymers for non-viral gene delivery using combinatorial approaches.Effects of base polymer hydrophobicity and end-group modification on polymeric gene delivery Niemann-Pick C1 affects the gene delivery efficacy of degradable polymeric nanoparticles.Gene delivery nanoparticles specific for human microvasculature and macrovasculature.2011 Rita Schaffer lecture: nanoparticles for intracellular nucleic acid delivery.Poly(β-amino ester)-nanoparticle mediated transfection of retinal pigment epithelial cells in vitro and in vivo.Development of poly(β-amino ester)-based biodegradable nanoparticles for nonviral delivery of minicircle DNA.Non-viral gene delivery nanoparticles based on poly(β-amino esters) for treatment of glioblastoma.Polymeric nanoparticles for nonviral gene therapy extend brain tumor survival in vivo.Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells Transfecting the hard-to-transfect lymphoma/leukemia cells using a simple cationic polymer nanocomplex.Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity Cystamine-terminated poly(beta-amino ester)s for siRNA delivery to human mesenchymal stem cells and enhancement of osteogenic differentiation.Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain.Poly(β-amino ester) nanoparticle delivery of TP53 has activity against small cell lung cancer in vitro and in vivo.Nanoparticle-mediated conversion of primary human astrocytes into neurons and oligodendrocytes The transition from linear to highly branched poly(β-amino ester)s: Branching matters for gene delivery.(3-aminopropyl)-4-methylpiperazine end-capped poly(1,4-butanediol diacrylate-co-4-amino-1-butanol)-based multilayer films for gene delivery.The effect and role of carbon atoms in poly(β-amino ester)s for DNA binding and gene delivery.Student award winner in the Ph.D. category for the 2013 society for biomaterials annual meeting and exposition, april 10-13, 2013, Boston, Massachusetts : biomaterial-mediated cancer-specific DNA delivery to liver cell cultures using synthetic poly(Programming stem cells for therapeutic angiogenesis using biodegradable polymeric nanoparticles.Drug delivery strategies for therapeutic angiogenesis and antiangiogenesis.Advances in polymeric and inorganic vectors for nonviral nucleic acid delivery.Smart chemistry in polymeric nanomedicine.Nanotherapeutic systems for local treatment of brain tumors.Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival Evaluation of polymeric gene delivery nanoparticles by nanoparticle tracking analysis and high-throughput flow cytometry.A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery.Enhancing oligodendrocyte differentiation by transient transcription activation via DNA nanoparticle-mediated transfection.Scaffold-mediated BMP-2 minicircle DNA delivery accelerated bone repair in a mouse critical-size calvarial defect model.Non-viral gene delivery via membrane-penetrating, mannose-targeting supramolecular self-assembled nanocomplexes.Degradable terpolymers with alkyl side chains demonstrate enhanced gene delivery potency and nanoparticle stability.Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.Polymeric nanoparticle-based delivery of TRAIL DNA for cancer-specific killing.

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Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

http://www.wikidata.org/entity/Q35233401

description

2009 nî lūn-bûn

@nan

2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

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Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

@en

type

label

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

@ast

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

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prefLabel

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

@ast

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

@en

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Advanced Materials

P1476

Small Molecule End Group of Linear Polymer Determines Cell-type Gene Delivery Efficacy

@en

P2093

Ahmed A Eltoukhy

http://www.w3.org/2001/XMLSchema#string

Daniel G Anderson

http://www.w3.org/2001/XMLSchema#string

David N Nguyen

http://www.w3.org/2001/XMLSchema#string

Fan Yang

http://www.w3.org/2001/XMLSchema#string

Kerry P Mahon

http://www.w3.org/2001/XMLSchema#string

P2860

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library.

Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).

Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery.

A polymer library approach to suicide gene therapy for cancer.

Biodegradable polymeric vectors for gene delivery to human endothelial cells.

A combinatorial polymer library approach yields insight into nonviral gene delivery

Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives.

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy.

Nanoparticulate delivery of diphtheria toxin DNA effectively kills Mesothelin expressing pancreatic cancer cells

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4947-4951

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scholarly article

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10.1002/ADMA.200901718

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P433

48

http://www.w3.org/2001/XMLSchema#string

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21

http://www.w3.org/2001/XMLSchema#string

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Joel C Sunshine

Robert Samuel Langer, Jr.

P577

2009-12-01T00:00:00Z

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P5875

264681135

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P698

25165411

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4143259

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