Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence - Wikidata - wikimedia - TriplyDB

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

http://www.wikidata.org/entity/Q35237992

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Meta-analysis and imputation refines the association of 15q25 with smoking quantity Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes Nicotinic acetylcholine receptors: upregulation, age-related effects and associations with drug use Updates on the COPD gene list The genetics of substance dependence From men to mice: CHRNA5/CHRNA3, smoking behavior and disease A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.The role of the habenula in drug addiction.Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.Alternative CHRNB4 3'-UTRs mediate the allelic effects of SNP rs1948 on gene expression Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism.New insights into the genetics of addiction Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice.Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice.Subtypes of nicotinic acetylcholine receptors in nicotine reward, dependence, and withdrawal: evidence from genetically modified mice.The alpha 3 subunit gene of the nicotinic acetylcholine receptor is a candidate gene for ethanol stimulation Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls.Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior.Identification of CHRNA5 rare variants in African-American heavy smokers CHRNA5 and CHRNA3 variants and level of neuroticism in young adult Mexican American men and women.Genetics and genomics of alcohol sensitivity Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking.Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.Mechanisms and genetic factors underlying co-use of nicotine and alcohol or other drugs of abuse.Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats.The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample.The Genetics, Neurogenetics and Pharmacogenetics of Addiction Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Smoking related cancers and loci at chromosomes 15q25, 5p15, 6p22.1 and 6p21.33 in the Polish population.The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer CHRNA5 variants moderate the effect of nicotine deprivation on a neural index of cognitive control Neuronal nicotinic acetylcholine receptors: common molecular substrates of nicotine and alcohol dependence.Nicotinic α5 receptor subunit mRNA expression is associated with distant 5' upstream polymorphisms.Scientific overview: 2013 BBC plenary symposium on tobacco addiction.Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease.A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia.Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.

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Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

http://www.wikidata.org/entity/Q35237992

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2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008年の論文

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Genetic variation in the CHRNA ...... th risk for alcohol dependence

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Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)

Haploview: analysis and visualization of LD and haplotype maps

Transcriptional regulation of the human alpha5 nicotinic receptor subunit gene in neuronal and non-neuronal tissues

alpha 5 Subunit alters desensitization, pharmacology, Ca++ permeability and Ca++ modulation of human neuronal alpha 3 nicotinic receptors

Neuronal nicotinic receptors: from structure to pathology

Novel genes identified in a high-density genome wide association study for nicotine dependence

Human neuronal nicotinic receptors.

Genetic analysis of genome-wide variation in human gene expression

Nicotinic Acetylcholine Receptors of Muscles and Nerves

Processing of gene expression data generated by quantitative real-time RT-PCR.

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