Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
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Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3Nuclear receptor corepressors and PPARgammaIs the Mouse a Good Model of Human PPARγ-Related Metabolic Diseases?Hydroxycinnamic acid derivatives: a potential class of natural compounds for the management of lipid metabolism and obesityRoad to exercise mimetics: targeting nuclear receptors in skeletal musclePerinatal overnutrition exacerbates adipose tissue inflammation caused by high-fat feeding in C57BL/6J mice'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic StudiesPAS kinase is required for normal cellular energy balancePPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.Ablation of ARNT/HIF1beta in liver alters gluconeogenesis, lipogenic gene expression, and serum ketonesSkeletal Muscle Nucleo-Mitochondrial Crosstalk in Obesity and Type 2 Diabetes.The contribution of visceral fat to improved insulin signaling in Ames dwarf mice.Nuclear receptors, mitochondria and lipid metabolismCompensation by the muscle limits the metabolic consequences of lipodystrophy in PPAR gamma hypomorphic mice.Role of Nuclear Receptors in Exercise-Induced Muscle Adaptations.Involvement of inducible 6-phosphofructo-2-kinase in the anti-diabetic effect of peroxisome proliferator-activated receptor gamma activation in mice.Hepatic FoxO1 ablation exacerbates lipid abnormalities during hyperglycemiaPeroxisome proliferator-activated receptor-gamma: too much of a good thing causes harmSignaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin.Pulmonary hypertension and metabolic syndrome: Possible connection, PPARγ and Caveolin-1Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver.Analysis of gene expression in pathophysiological states: balancing false discovery and false negative rates.Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes.Monogenic syndromes of abnormal glucose homeostasis: clinical review and relevance to the understanding of the pathology of insulin resistance and beta cell failure.PPAR gamma and human metabolic diseaseMolecular Implications of the PPARs in the Diabetic Eye.Revisiting PPARγ as a target for the treatment of metabolic disordersThe peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro.The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoformPKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.PPAR-gamma expression modulates insulin sensitivity in C2C12 skeletal muscle cellsHepatic glucose intolerance precedes hepatic steatosis in the male aromatase knockout (ArKO) mouse.PPARγ: a circadian transcription factor in adipogenesis and osteogenesis.Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation.Muscle as a "mediator" of systemic metabolismBeneficial effects of subcutaneous fat transplantation on metabolismDepletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish.Ginseng berry extract supplementation improves age-related decline of insulin signaling in mice.Respective contributions of maternal insulin resistance and diet to metabolic and hypothalamic phenotypes of progeny
P2860
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P2860
Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@ast
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@en
type
label
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@ast
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@en
prefLabel
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@ast
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@en
P2093
P2860
P50
P356
P1476
Muscle-specific PPARgamma-defi ...... respond to thiazolidinediones.
@en
P2093
Alison C Jozsi
Evan D Rosen
Frank J Gonzalez
Ildiko Szanto
Laurie J Goodyear
Lihong Chen
Michael F Hirshman
Simon J Fisher
P2860
P304
P356
10.1172/JCI17305
P407
P577
2003-08-01T00:00:00Z