Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form
about
Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretionDisorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretionAlbumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin.The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies.Structural Characterization of Humanized Nanobodies with Neutralizing Activity against the Bordetella pertussis CyaA-Hemolysin: Implications for a Potential Epitope of Toxin-Protective AntigenExposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.Negatively charged residues of the segment linking the enzyme and cytolysin moieties restrict the membrane-permeabilizing capacity of adenylate cyclase toxin.The conserved tyrosine residue 940 plays a key structural role in membrane interaction of Bordetella adenylate cyclase toxin.Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes.Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.Revealing how an adenylate cyclase toxin uses bait and switch tactics in its activation.Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding
P2860
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P2860
Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form
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2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@ast
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@en
type
label
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@ast
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@en
prefLabel
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@ast
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@en
P2093
P2860
P356
P1476
Calcium, acylation, and molecu ...... a monomeric and cytotoxic form
@en
P2093
Audrey Hessel
Johanna C Karst
Orso Subrini
Sara E Cannella
Sylvain Debard
V Yvette Ntsogo Enguéné
P2860
P304
30702-30716
P356
10.1074/JBC.M114.580852
P407
P577
2014-09-17T00:00:00Z