Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy
about
Swing-out of the β3 hybrid domain is required for αIIbβ3 priming and normal cytoskeletal reorganization, but not adhesion to immobilized fibrinogenCross-Scale Integrin Regulation Organizes ECM and Tissue Topology.Complete integrin headpiece opening in eight stepsThree-dimensional reconstruction of intact human integrin IIb 3: new implications for activation-dependent ligand bindingThe cancer glycocalyx mechanically primes integrin-mediated growth and survivalTargeting integrin and integrin signaling in treating thrombosis.αIIbβ3 variants defined by next-generation sequencing: predicting variants likely to cause Glanzmann thrombasthenia.Integrin inside-out signaling and the immunological synapseA single disulfide bond disruption in the β3 integrin subunit promotes thiol/disulfide exchange, a molecular dynamics study.The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological LigandResolving two-dimensional kinetics of the integrin αIIbβ3-fibrinogen interactions using binding-unbinding correlation spectroscopyGlycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo.β-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbβ3 Headpiece.αIIbβ3: structure and functionRelating conformation to function in integrin α5β1.Integrin bi-directional signaling across the plasma membrane.Protein conformation as a regulator of cell-matrix adhesion.Extracellular matrix biomimicry for the creation of investigational and therapeutic devices.Recent advances in nanodisc technology for membrane protein studies (2012-2017).Force interacts with macromolecular structure in activation of TGF-βTalin-driven inside-out activation mechanism of platelet αIIbβ3 integrin probed by multimicrosecond, all-atom molecular dynamics simulations.A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression.Expanding the Mutation Spectrum Affecting αIIbβ3 Integrin in Glanzmann Thrombasthenia: Screening of the ITGA2B and ITGB3 Genes in a Large International Cohort.Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Cryo-Microscopy.Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and ActivationMolecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation
P2860
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P2860
Intact alphaIIbbeta3 integrin is extended after activation as measured by solution X-ray scattering and electron microscopy
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@ast
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@en
type
label
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@ast
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@en
prefLabel
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@ast
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@en
P2093
P2860
P356
P1476
Intact alphaIIbbeta3 integrin ...... tering and electron microscopy
@en
P2093
Benoit J Smagghe
Edward T Eng
Thomas Walz
Timothy A Springer
P2860
P304
35218-35226
P356
10.1074/JBC.M111.275107
P407
P577
2011-08-09T00:00:00Z