Deletion of Syk in neutrophils prevents immune complex arthritis - Wikidata - wikimedia - TriplyDB

Deletion of Syk in neutrophils prevents immune complex arthritis

Deletion of Syk in neutrophils prevents immune complex arthritis

http://www.wikidata.org/entity/Q35269028

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K/BxN Serum-Transfer Arthritis as a Model for Human Inflammatory Arthritis Targeting Syk in Autoimmune Rheumatic Diseases A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation Saposin C coupled lipid nanovesicles specifically target arthritic mouse joints for optical imaging of disease severity Neutrophil cell surface receptors and their intracellular signal transduction pathways.Mechanisms of Autoantibody-Induced Pathology.Getting Syk: spleen tyrosine kinase as a therapeutic target.Gene expression during the generation and activation of mouse neutrophils: implication of novel functional and regulatory pathways.Heme oxygenase-1 regulates the progression of K/BxN serum transfer arthritis.The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.The neuropeptide neuromedin U promotes autoantibody-mediated arthritis.MET is required for the recruitment of anti-tumoural neutrophils Endoplasmic Reticulum Stress of Neutrophils Is Required for Ischemia/Reperfusion-Induced Acute Lung Injury.Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.New models for analyzing mast cell functions in vivo.Approaches for analyzing the roles of mast cells and their proteases in vivo.Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.Neutrophils in animal models of autoimmune disease Immune Defense Protein Expression in Highly Purified Mouse Lung Epithelial Cells.Neutrophils mediate antibody-induced antitumor effects in mice.PTPN22 Is a Critical Regulator of Fcγ Receptor-Mediated Neutrophil Activation Lipid-cytokine-chemokine cascades orchestrate leukocyte recruitment in inflammation Neutrophils in innate and adaptive immunity.Intracellular signalling during neutrophil recruitment.TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression.PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide.The Syk Tyrosine Kinase Is Required for Skin Inflammation in an In Vivo Mouse Model of Epidermolysis Bullosa Acquisita Altered BCR signalling quality predisposes to autoimmune disease and a pre-diabetic state.Mast cell promotion of T cell-driven antigen-induced arthritis despite being dispensable for antibody-induced arthritis in which T cells are bypassed.Lineage-Specific Analysis of Syk Function in Autoantibody-Induced Arthritis.Syk-dependent signaling pathways in neutrophils and macrophages are indispensable in the pathogenesis of anti-collagen antibody-induced arthritis.

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Deletion of Syk in neutrophils prevents immune complex arthritis

http://www.wikidata.org/entity/Q35269028

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Deletion of Syk in neutrophils prevents immune complex arthritis

@ast

Deletion of Syk in neutrophils prevents immune complex arthritis

@en

type

label

Deletion of Syk in neutrophils prevents immune complex arthritis

@ast

Deletion of Syk in neutrophils prevents immune complex arthritis

@en

prefLabel

Deletion of Syk in neutrophils prevents immune complex arthritis

@ast

Deletion of Syk in neutrophils prevents immune complex arthritis

@en

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JIMMUNOL.1100341

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Journal of Immunology

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Deletion of Syk in neutrophils prevents immune complex arthritis

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Brandon M Sullivan

http://www.w3.org/2001/XMLSchema#string

Clifford A Lowell

http://www.w3.org/2001/XMLSchema#string

Emily R Elliott

http://www.w3.org/2001/XMLSchema#string

Jessica A Van Ziffle

http://www.w3.org/2001/XMLSchema#string

Patrizia Scapini

http://www.w3.org/2001/XMLSchema#string

Richard M Locksley

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P2860

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development

Regulation of developmental lymphangiogenesis by Syk(+) leukocytes

Mast cell-deficient W-sash c-kit mutant Kit W-sh/W-sh mice as a model for investigating mast cell biology in vivo

Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.

Neutrophil-specific deletion of Syk kinase results in reduced host defense to bacterial infection

Neutrophils and immunity: challenges and opportunities

Neutrophil granules: a library of innate immunity proteins.

Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases

Pathways: Strategies for susceptibility genes in SLE.

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21918195

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3186826

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