TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR - Wikidata - wikimedia - TriplyDB

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

http://www.wikidata.org/entity/Q35273064

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Organization of the human tarbp2 gene reveals two promoters that are repressed in an astrocytic cell line Interaction of human tRNA-dihydrouridine synthase-2 with interferon-induced protein kinase PKR PACT, a protein activator of the interferon-induced protein kinase, PKR.The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domains The C-terminal, third conserved motif of the protein activator PACT plays an essential role in the activation of double-stranded-RNA-dependent protein kinase (PKR)Modular structure of PACT: distinct domains for binding and activating PKR A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells Dual role of TRBP in HIV replication and RNA interference: viral diversion of a cellular pathway or evasion from antiviral immunity?Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5A RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression Merlin, a tumor suppressor, interacts with transactivation-responsive RNA-binding protein and inhibits its oncogenic activity Schwannomin inhibits tumorigenesis through direct interaction with the eukaryotic initiation factor subunit c (eIF3c)The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development Recombinant hTRBP and hPACT Modulate hAgo2-Catalyzed siRNA-Mediated Target RNA Cleavage In Vitro HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR Regulation of fibroblast growth factor-2 by an endogenous antisense RNA and by argonaute-2.Diminished production of human immunodeficiency virus type 1 in astrocytes results from inefficient translation of gag, env, and nef mRNAs despite efficient expression of Tat and Rev Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.Co-expression of miRNA targeting the expression of PERK, but not PKR, enhances cellular immunity from an HIV-1 Env DNA vaccine.Exchange of the basic domain of human immunodeficiency virus type 1 Rev for a polyarginine stretch expands the RNA binding specificity, and a minimal arginine cluster is required for optimal RRE RNA binding affinity, nuclear accumulation, and trans-Double-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18 Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.HIV-l and the microRNA-guided silencing pathway: an intricate and multifaceted encounter Antisense RNA: function and fate of duplex RNA in cells of higher eukaryotes.Emergence of a complex relationship between HIV-1 and the microRNA pathway.Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response.Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes miRNAs at the interface of cellular stress and disease Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila.MicroRNAs in gene regulation: when the smallest governs it all A critical role for PKR complexes with TRBP in Immunometabolic regulation and eIF2α phosphorylation in obesity Quantifying the Antiviral Effect of IFN on HIV-1 Replication in Cell Culture Rescue of vaccinia virus lacking the E3L gene by mutants of E3L.cis-acting elements in human immunodeficiency virus type 1 RNAs direct viral transcripts to distinct intranuclear locations.

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TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

http://www.wikidata.org/entity/Q35273064

description

1994 nî lūn-bûn

@nan

1994 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

1994 թվականի մայիսին հրատարակված գիտական հոդված

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1994年の論文

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1994年論文

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1994年論文

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1994年論文

@zh-hk

1994年論文

@zh-mo

1994年論文

@zh-tw

1994年论文

@wuu

name

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@ast

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@en

type

label

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@ast

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@en

prefLabel

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@ast

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@en

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PNAS.91.11.4713

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Proceedings of the National Academy of Sciences of the United States of America

P1476

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

@en

P2093

Chang HW

http://www.w3.org/2001/XMLSchema#string

Davies MV

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Jacobs BL

http://www.w3.org/2001/XMLSchema#string

Kaufman RJ

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Langland JO

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Nam YS

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Paoletti E

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Park H

http://www.w3.org/2001/XMLSchema#string

Tartaglia J

http://www.w3.org/2001/XMLSchema#string

Venkatesan S

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

The E3L gene of vaccinia virus encodes an inhibitor of the interferon-induced, double-stranded RNA-dependent protein kinase

A conserved double-stranded RNA-binding domain

Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufen

The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast.

Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control

Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

Identification and characterization of a nuclear factor that specifically binds to the Rev response element (RRE) of human immunodeficiency virus type 1 (HIV-1)

Translational control in mammalian cells

P304

4713-4717

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10.1073/PNAS.91.11.4713

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11

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91

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1994-05-01T00:00:00Z

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15684284

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7515177

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43858

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