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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

http://www.wikidata.org/entity/Q35283020

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ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma Regulation of Differentiation by Calcium-Sensing Receptor in Normal and Tumoral Developing Nervous System NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?Energy metabolism in neuroblastoma and Wilms tumor Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma Natural killer cells and neuroblastoma: tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches Tumors of the neural crest: Common themes in development and cancer Pediatric solid tumor genomics and developmental pliancy TrkB/BDNF signalling patterns the sympathetic nervous system Novel ALK inhibitor AZD3463 inhibits neuroblastoma growth by overcoming crizotinib resistance and inducing apoptosis.Sparstolonin B, a novel plant derived compound, arrests cell cycle and induces apoptosis in N-myc amplified and N-myc nonamplified neuroblastoma cells Assessment of the chemosensitizing activity of TAT-RasGAP317-326 in childhood cancers Microenvironmental Modulation of Decorin and Lumican in Temozolomide-Resistant Glioblastoma and Neuroblastoma Cancer Stem-Like Cells JARID1B Expression Plays a Critical Role in Chemoresistance and Stem Cell-Like Phenotype of Neuroblastoma Cells Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation Neuroblastoma, a Paradigm for Big Data Science in Pediatric Oncology.Sialic acid metabolic engineering: a potential strategy for the neuroblastoma therapy.Genome-wide DNA methylation analysis identifies MEGF10 as a novel epigenetically repressed candidate tumor suppressor gene in neuroblastoma Inactivation of SMC2 shows a synergistic lethal response in MYCN-amplified neuroblastoma cells.Glycobiology of neuroblastoma: impact on tumor behavior, prognosis, and therapeutic strategies.Hyperactivation of Alk induces neonatal lethality in knock-in AlkF1178L mice Optimization of liposomal topotecan for use in treating neuroblastoma.Imaging the norepinephrine transporter in neuroblastoma: a comparison of [18F]-MFBG and 123I-MIBG.The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.PleiotRHOpic: Rho pathways are essential for all stages of Neural Crest development.Wild-type ALK and activating ALK-R1275Q and ALK-F1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells Feeder-free derivation of neural crest progenitor cells from human pluripotent stem cells.Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy.Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours.A Phase I Study of the Anti-Idiotype Vaccine Racotumomab in Neuroblastoma and Other Pediatric Refractory Malignancies.Essential role of GATA3 in regulation of differentiation and cell proliferation in SK-N-SH neuroblastoma cells Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells.Neuroblastoma in dialog with its stroma: NTRK1 is a regulator of cellular cross-talk with Schwann cells.Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.High-resolution array CGH profiling identifies Na/K transporting ATPase interacting 2 (NKAIN2) as a predisposing candidate gene in neuroblastoma A cell-based high-throughput screen addressing 3'UTR-dependent regulation of the MYCN gene.Bone marrow minimal residual disease was an early response marker and a consistent independent predictor of survival after anti-GD2 immunotherapy.Retargeting T cells to GD2 pentasaccharide on human tumors using Bispecific humanized antibody.Phosphatidylinositol 3-kinase, class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis The impact of S6K1 kinase on neuroblastoma cell proliferation is independent of GLI1 signaling

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Nature Reviews Cancer

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Neuroblastoma: developmental biology, cancer genomics and immunotherapy.

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Michael A Dyer

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Nai-Kong V Cheung

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P2860

Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine

Hallmarks of Cancer: The Next Generation

Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis

Interleukin-15 biology and its therapeutic implications in cancer

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

Identification of ALK as a major familial neuroblastoma predisposition gene

Chromosome 6p22 locus associated with clinically aggressive neuroblastoma

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10.1038/NRC3526

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