Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status - Wikidata - wikimedia - TriplyDB

Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status

Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status

http://www.wikidata.org/entity/Q35284879

about

TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma Metabolic interrogation as a tool to optimize chemotherapeutic regimens.Chemoradiation provides a physiological selective pressure that increases the expansion of aberrant TP53 tumor variants in residual rectal cancerous regions.Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis.Anti-tumor effects of metformin on head and neck carcinoma cell lines: A systematic review Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model.Metformin use and improved response to therapy in rectal cancer.Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation.Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time.Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53.Reactive oxygen species and p21Waf1/Cip1 are both essential for p53-mediated senescence of head and neck cancer cells.Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth.Inhibition of glucose transporter 1 (GLUT1) chemosensitized head and neck cancer cells to cisplatin.Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma.Targeting metabolism and AMP-activated kinase with metformin to sensitize non-small cell lung cancer (NSCLC) to cytotoxic therapy: translational biology and rationale for current clinical trials.Metformin effects on head and neck squamous carcinoma microenvironment: Window of opportunity trial.High-risk TP53 mutations are associated with extra nodal extension (ENE) in oral cavity squamous cell carcinoma (OSCC).Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism.Visualizing the effects of metformin on tumor growth, vascularity, and metabolism in head and neck cancer.

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Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status

http://www.wikidata.org/entity/Q35284879

description

2011 nî lūn-bûn

@nan

2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Individualizing antimetabolic ...... ased on TP53 mutational status

@ast

Individualizing antimetabolic ...... ased on TP53 mutational status

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type

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Individualizing antimetabolic ...... ased on TP53 mutational status

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Individualizing antimetabolic ...... ased on TP53 mutational status

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Individualizing antimetabolic ...... ased on TP53 mutational status

@en

P2093

Aijun Zhang

http://www.w3.org/2001/XMLSchema#string

Curtis R Pickering

http://www.w3.org/2001/XMLSchema#string

Ge Zhou

http://www.w3.org/2001/XMLSchema#string

Heath D Skinner

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James M Luchak

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Jeffrey N Myers

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Lee-Jun C Wong

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Thomas J Ow

http://www.w3.org/2001/XMLSchema#string

Vlad C Sandulache

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Xuefeng Xia

http://www.w3.org/2001/XMLSchema#string

P2860

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells

Understanding the Warburg effect: the metabolic requirements of cell proliferation

IDH1 and IDH2 mutations in gliomas

Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck

On the Origin of Cancer Cells

p53 regulates mitochondrial respiration

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water.

Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

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711-721

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scholarly article

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10.1002/CNCR.26321

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3

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118

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21720999

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