RNA enzymes (ribozymes) as antiviral therapeutic agents.

RNA enzymes (ribozymes) as antiviral therapeutic agents.

Item
http://www.wikidata.org/entity/Q35285900
A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1Gene discovery by ribozyme and siRNA libraries.Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III.Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cellsCell-type-specific aptamer and aptamer-small interfering RNA conjugates for targeted human immunodeficiency virus type 1 therapy.Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo.An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield.Convergent evolution of twintron-like configurations: One is never enough.Implications of ribozyme kinetics for targeting the cleavage of specific RNA molecules in vivo: more isn't always better.Negative electrospray ionization mass spectrometry of synthetic and chemically modified oligonucleotidesSelective cleavage of closely-related mRNAs by synthetic ribozymes.Chemical synthesis of RNA using fast oligonucleotide deprotection chemistry.Inhibition of gene expression with ribozymes.Antiviral ribozymes. New jobs for ancient molecules.Retrovirally expressed anti-HIV ribozymes confer a selective survival advantage on CD4+ T cells in vitro.
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RNA enzymes (ribozymes) as antiviral therapeutic agents.

Item
http://www.wikidata.org/entity/Q35285900
description
1990 nî lūn-bûn
@nan
1990 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@ast
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@en
type
label
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@ast
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@en
prefLabel
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@ast
RNA enzymes (ribozymes) as antiviral therapeutic agents.
@en
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RNA enzymes (ribozymes) as antiviral therapeutic agents.
@en
P2093
P304
P31
P356
10.1016/0167-7799(90)90169-X
P433
P478
P577
P698
P921