Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion. - Wikidata - wikimedia - TriplyDB

Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion.

Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion.

http://www.wikidata.org/entity/Q35287627

about

Exosomes from human colorectal cancer induce a tumor-like behavior in colonic mesenchymal stromal cells The cell survival pathways of the primordial RNA-DNA complex remain conserved in the extant genomes and may function as proto-oncogenes The emergence of extracellular vesicles in urology: fertility, cancer, biomarkers and targeted pharmacotherapy.Exosomes in cancer: small particle, big player.Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer.Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium Distinct Small RNA Signatures in Extracellular Vesicles Derived from Breast Cancer Cell Lines Tumor Cell-Derived Exosomes from the Prostate Cancer Cell Line TRAMP-C1 Impair Osteoclast Formation and Differentiation.Telomeric repeat-containing RNA (TERRA) constitutes a nucleoprotein component of extracellular inflammatory exosomes.Quantification of plasma exosome is a potential prognostic marker for esophageal squamous cell carcinoma.Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein.Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction.Extracellular vesicles such as prostate cancer cell fragments as a fluid biopsy for prostate cancer.The origin of prostate metastases: emerging insights.Exosomal HSP60: a potentially useful biomarker for diagnosis, assessing prognosis, and monitoring response to treatment.The multifaceted role of extracellular vesicles in metastasis: Priming the soil for seeding.Exosomal particles secreted by prostate cancer cells are potent mRNA and protein vehicles for the interference of tumor and tumor environment.Differential expression of ligands for NKG2D and DNAM-1 receptors by epithelial ovarian cancer-derived exosomes and its influence on NK cell cytotoxicity.Cell-free microRNAs in blood and other body fluids, as cancer biomarkers.Exosomal transfer of vasorin expressed in hepatocellular carcinoma cells promotes migration of human umbilical vein endothelial cells.Exosomes: From Functions in Host-Pathogen Interactions and Immunity to Diagnostic and Therapeutic Opportunities.Functions of Cancer-Derived Extracellular Vesicles in Immunosuppression.The emerging role of exosome and microvesicle- (EMV-) based cancer therapeutics and immunotherapy.Extracellular Vesicles from Metastatic Rat Prostate Tumors Prime the Normal Prostate Tissue to Facilitate Tumor Growth.Regulation of NKG2D+CD8+ T-cell-mediated antitumor immune surveillance: Identification of a novel CD28 activation-mediated, STAT3 phosphorylation-dependent mechanism.NKG2D ligand expression in Crohn's disease and NKG2D-dependent stimulation of CD8+ T cell migration Anti-NKG2D mAb: A New Treatment for Crohn's Disease?Highly aggressive rat prostate tumors rapidly precondition regional lymph nodes for subsequent metastatic growth.Biological roles and potential applications of immune cell-derived extracellular vesicles.Molecular determinants of prostate cancer metastasis.Exosomes in diagnosis and therapy of prostate cancer.Proteomic Profiling of Secreted Proteins, Exosomes, and Microvesicles in Cell Culture Conditioned Media.Placental exosomes: A proxy to understand pregnancy complications.Stroma-derived extracellular vesicles deliver tumor-suppressive miRNAs to pancreatic cancer cells.Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy.Exosome-Based Cell-Cell Communication in the Tumor Microenvironment.Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells.Exosomes in melanoma: a role in tumor progression, metastasis and impaired immune system activity.Cancer-derived extracellular vesicles: friend and foe of tumour immunosurveillance.Immune phenotypes of prostate cancer cells: Evidence of epithelial immune cell-like transition?

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P2860

Prostate tumor-derived exosomes down-regulate NKG2D expression on natural killer cells and CD8+ T cells: mechanism of immune evasion.

http://www.wikidata.org/entity/Q35287627

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Prostate tumor-derived exosome ...... : mechanism of immune evasion.

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Anders Widmark

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Lucia Mincheva-Nilsson

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Marie Lundholm

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Mona Schröder

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Olga Nagaeva

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Pernilla Wikström

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Vladimir Baranov

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P2860

Exosomes as a tumor immune escape mechanism: possible therapeutic implications

Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB

An activating immunoreceptor complex formed by NKG2D and DAP10

Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes

Exosomal-like vesicles are present in human blood plasma

The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Functional delivery of viral miRNAs via exosomes

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