E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
about
Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza A virus.Recent progress in structure-based anti-influenza drug designOrganization of the influenza virus replication machineryMonomeric Nucleoprotein of Influenza A VirusStructural Basis for RNA Binding and Homo-Oligomer Formation by Influenza B Virus NucleoproteinThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignTwo birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicineA Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus NucleoproteinIdentification of influenza A nucleoprotein body domain residues essential for viral RNA expression expose antiviral target.CNOT4-Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication.Emerging antiviral resistant strains of influenza A and the potential therapeutic targets within the viral ribonucleoprotein (vRNP) complex.Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization.Reduction of false positives in structure-based virtual screening when receptor plasticity is considered.Phosphorylation at the homotypic interface regulates nucleoprotein oligomerization and assembly of the influenza virus replication machineryStructure-based design of novel naproxen derivatives targeting monomeric nucleoprotein of Influenza A virus.Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches.Influenza B virus non-structural protein 1 counteracts ISG15 antiviral activity by sequestering ISGylated viral proteins.Recent advances in pharmacophore modeling and its application to anti-influenza drug discovery.New-generation screening assays for the detection of anti-influenza compounds targeting viral and host functions.Influenza virus nucleoprotein: structure, RNA binding, oligomerization and antiviral drug target.Antiviral strategies against influenza virus: towards new therapeutic approaches.Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza.Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development.The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.Influenza A Virus Nucleoprotein: A Highly Conserved Multi-Functional Viral Protein as a Hot Antiviral Drug Target.Oligomerization of the carboxyl terminal domain of the human coronavirus 229E nucleocapsid protein.The role and assembly mechanism of nucleoprotein in influenza A virus ribonucleoprotein complexes.Versatility and invariance in the evolution of homologous heteromeric interfaces.Identification of a novel compound targeting the nuclear export of influenza A virus nucleoprotein.
P2860
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P2860
E339...R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@ast
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@en
type
label
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@ast
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@en
prefLabel
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@ast
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@en
P2093
P2860
P356
P1476
E339...R416 salt bridge of nuc ...... for influenza virus inhibitors
@en
P2093
Chao-Jung Wu
Chi-Huey Wong
Fu-Yang Lin
Gialih Lin
Hua-Ting Hsu
Hui-Wen Liu
Meng-I Lin
Pang-Hung Hsu
Shao-Ying Chu
P2860
P304
16515-16520
P356
10.1073/PNAS.1113107108
P407
P577
2011-09-19T00:00:00Z