ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding

ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding

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http://www.wikidata.org/entity/Q35310662
Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause DwarfismA functional screen provides evidence for a conserved, regulatory, juxtamembrane phosphorylation site in guanylyl cyclase a and B.Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes.Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature.Guanylyl cyclases A and B are asymmetric dimers that are allosterically activated by ATP binding to the catalytic domain.A human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B.Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes.Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone.
P2860

ATP potentiates competitive inhibition of guanylyl cyclase A and B by the staurosporine analog, Gö6976: reciprocal regulation of ATP and GTP binding

Item
http://www.wikidata.org/entity/Q35310662
description
2011 nî lūn-bûn
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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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name
ATP potentiates competitive in ...... ulation of ATP and GTP binding
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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P1433
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ATP potentiates competitive in ...... ulation of ATP and GTP binding
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P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932