Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway.
about
E-type prostanoid receptor 4 (EP4) in disease and therapyThe tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin.Prostaglandin receptors EP1-4 as a potential marker for clinical outcome in urothelial bladder cancer.Rap1GAP regulates renal cell carcinoma invasion.Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA.PGE2 promotes renal carcinoma cell invasion through activated RalA.Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis.Non-steroid anti-inflammatory drugs, prostaglandins, and cancer.Prostaglandin E receptor EP4 is a therapeutic target in breast cancer cells with stem-like properties.Combined targeting of STAT3/NF-κB/COX-2/EP4 for effective management of pancreatic cancer.Low expression of Rap1GAP is associated with epithelial-mesenchymal transition (EMT) and poor prognosis in gastric cancer.Roles of Rap1 signaling in tumor cell migration and invasionThe role of prostaglandin E2 in renal cell cancer development: future implications for prognosis and therapy.Prostaglandin E2 stimulates urokinase-type plasminogen activator receptor via EP2 receptor-dependent signaling pathways in human AGS gastric cancer cells.High SIPA-1 expression in proximal tubules of human kidneys under pathological conditions.An EP4 antagonist ONO-AE3-208 suppresses cell invasion, migration, and metastasis of prostate cancer.Silymarin suppresses the PGE2 -induced cell migration through inhibition of EP2 activation; G protein-dependent PKA-CREB and G protein-independent Src-STAT3 signal pathways.Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis.
P2860
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P2860
Prostaglandin E2 regulates renal cell carcinoma invasion through the EP4 receptor-Rap GTPase signal transduction pathway.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@ast
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@en
type
label
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@ast
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@en
prefLabel
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@ast
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@en
P2093
P2860
P356
P1476
Prostaglandin E2 regulates ren ...... e signal transduction pathway.
@en
P2093
Juanjuan Wu
Nicole Frilot
Wan-Ju Kim
Yehia Daaka
Yushan Zhang
P2860
P304
33954-33962
P356
10.1074/JBC.M110.187344
P407
P577
2011-08-10T00:00:00Z