Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
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An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteinsAcetyl-CoA the key factor for survival or death of cholinergic neurons in course of neurodegenerative diseasesRecent advances in the application of metabolomics to Alzheimer's DiseaseActive transport of acetylcholine by the human vesicular acetylcholine transporterIdentification and characterization of the high-affinity choline transporterRescue of easily shocked mutant seizure sensitivity in Drosophila adults.Repeated, intermittent exposures to diisopropylfluorophosphate in rats: protracted effects on cholinergic markers, nerve growth factor-related proteins, and cognitive function.A guide to the metabolic pathways and function of metabolites observed in human brain 1H magnetic resonance spectra.Characterization of the blood-brain barrier choline transporter using the in situ rat brain perfusion technique.Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease.The choline-leakage hypothesis for the loss of acetylcholine in Alzheimer's disease.Apolipoprotein E in the brain and its role in Alzheimer's disease.Do susceptibility loci contribute to the expression of more than one mental disorder? A view from the genetics of Alzheimer's disease.Overexpression of the high affinity choline transporter in cortical regions affected by Alzheimer's disease. Evidence from rapid autopsy studiesSynthesis and characterization of luminescent cadmium selenide/zinc selenide/zinc sulfide cholinomimetic quantum dots.Exploring temporospatial changes in glucose metabolic disorder, learning, and memory dysfunction in a rat model of diffuse axonal injury.Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody.Neurotransmitter transporters. A novel family of integral plasma membrane proteins.The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring CohortInteractions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease.Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degenerationAging modifies brain region-specific vulnerability to experimental oxidative stress induced by low dose hydrogen peroxide.Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth.Effects of Perfluorooctanoic Acid on Metabolic Profiles in Brain and Liver of Mouse Revealed by a High-throughput Targeted Metabolomics Approach.Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice.The return of the cholinergic hypothesisEffects of pro-inflammatory cytokines on apolipoprotein E secretion by a human astrocytoma cell line (CCF-STTG1).High affinity choline transporter status in Alzheimer's disease tissue from rapid autopsy.Apolipoprotein E, synaptic plasticity and Alzheimer's disease.Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients.Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.Amyloid beta-peptide 25-35 reduces [3H]acetylcholine release in retinal neurons. Involvement of metabolic dysfunction.Role of high-affinity choline uptake on extracellular choline and acetylcholine evoked by NMDA.Cortical choline transporter function measured in vivo using choline-sensitive microelectrodes: clearance of endogenous and exogenous choline and effects of removal of cholinergic terminals.Alterations of acetylcholinesterase activity after traumatic brain injury in rats.Restoration of blood pressure by choline treatment in rats made hypotensive by haemorrhageDifferential routing of choline in implanted breast cancer and normal organs.CDP-choline significantly restores phosphatidylcholine levels by differentially affecting phospholipase A2 and CTP: phosphocholine cytidylyltransferase after stroke.Functional Vitamin E deficiency in ApoE4 patients with Alzheimer's disease.Choline and Choline alphoscerate Do Not Modulate Inflammatory Processes in the Rat Brain.
P2860
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P2860
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
description
1992 nî lūn-bûn
@nan
1992 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@ast
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@en
type
label
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@ast
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@en
prefLabel
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@ast
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@en
P1476
Choline metabolism as a basis for the selective vulnerability of cholinergic neurons.
@en
P2093
R J Wurtman
P304
P356
10.1016/0166-2236(92)90351-8
P577
1992-04-01T00:00:00Z