Nuclear initiated NF-κB signaling: NEMO and ATM take center stage. - Wikidata - wikimedia - TriplyDB

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

http://www.wikidata.org/entity/Q35347865

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LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO DNA damage, tumor mutational load and their impact on immune responses against cancer Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy Hypoxia Induced NF-κB When ubiquitin meets NF-κB: a trove for anti-cancer drug development Homeodomain-Interacting Protein Kinase-2: A Critical Regulator of the DNA Damage Response and the Epigenome Systemic DNA damage responses in aging and diseases Binding Site Configurations Probe the Structure and Dynamics of the Zinc Finger of NEMO (NF-κB Essential Modulator).Diet components can suppress inflammation and reduce cancer risk.Chronic inflammation induces telomere dysfunction and accelerates ageing in mice.The combined effects of irradiation and herpes simplex virus type 1 infection on an immortal gingival cell line.BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.DEAD-box helicase DP103 defines metastatic potential of human breast cancers.Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress.A novel non-coding RNA lncRNA-JADE connects DNA damage signalling to histone H4 acetylation.Listeria monocytogenes dampens the DNA damage response Novel approaches in anaplastic thyroid cancer therapy An S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.cAMP signaling inhibits radiation-induced ATM phosphorylation leading to the augmentation of apoptosis in human lung cancer cells Human cytomegalovirus gene UL76 induces IL-8 expression through activation of the DNA damage response.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis Move or die: the fate of the Tax oncoprotein of HTLV-1.Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1.Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila.IKK biology.Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1 MicroRNA-155 is required for Mycobacterium bovis BCG-mediated apoptosis of macrophages Ursolic acid from Trailliaedoxa gracilis induces apoptosis in medullary thyroid carcinoma cells.The canonical NF-κB pathway differentially protects normal and human tumor cells from ROS-induced DNA damage Persistent Activation of the Innate Immune Response in Adult Drosophila Following Radiation Exposure During Larval Development.Shenqi fuzheng injection attenuates irradiation-induced brain injury in mice via inhibition of the NF-κB signaling pathway and microglial activation.A BRCA1-interacting lncRNA regulates homologous recombination.Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines NF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug.Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas.Bclaf1 is an important NF-κB signaling transducer and C/EBPβ regulator in DNA damage-induced senescence.Lymphocyte development: integration of DNA damage response signaling.DNA damage drives accelerated bone aging via an NF-κB-dependent mechanism.Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation.

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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

http://www.wikidata.org/entity/Q35347865

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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type

label

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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prefLabel

Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.

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Shigeki Miyamoto

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P2860

Structure of an IkappaBalpha/NF-kappaB complex

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

Activation of transcription factor NF-kappaB requires ELKS, an IkappaB kinase regulatory subunit

Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death

SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processing

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress

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10.1038/CR.2010.179

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