Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer
about
Single and Multiple Gene Manipulations in Mouse Models of Human CancerThe double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformationMetformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation.Krüppel-like factor 5 protects against murine colitis and activates JAK-STAT signaling in vivo.Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells.Klf5 deletion promotes Pten deletion-initiated luminal-type mouse prostate tumors through multiple oncogenic signaling pathwaysRestoring KLF5 in esophageal squamous cell cancer cells activates the JNK pathway leading to apoptosis and reduced cell survival.Squamous Cell Cancers: A Unified Perspective on Biology and GeneticsRegulation of hypoxia-inducible factor 1α (HIF-1α) by lysophosphatidic acid is dependent on interplay between p53 and Krüppel-like factor 5.KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelial-mesenchymal transition in epithelial cells.Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.Krüppel-like factors in hepatocellular carcinoma.Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients.Kruppel-like Pluripotency Factors as Modulators of Cancer Cell Therapeutic Responses.Personalized and targeted therapy of esophageal squamous cell carcinoma: an updateSP and KLF Transcription Factors in Digestive Physiology and Diseases.p53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation.KLF4 is downregulated but not mutated during human esophageal squamous cell carcinogenesis and has tumor stage-specific functions.KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification.
P2860
Q26783920-45C5B620-5733-4BAA-97C9-79181D5002B7Q27022848-CD7420DC-D3DD-4A3D-A74B-1730174F8909Q33577449-45532F66-CBD8-4E80-B1CB-B9E1DE020202Q34295488-E0C33358-E7DB-4405-B164-7EDA69F25359Q34514009-BF5DE4F2-B7D1-419C-BA12-45B0C011F39CQ34558936-2AAA1722-1947-425F-9F24-502E93F97C68Q36801079-0865FC10-A4E7-46D1-80AC-5E131AE62EDAQ36909843-2DBAF391-52C2-4662-A21E-33DB811915E6Q37132090-FA2DAF6E-C4EB-4DDD-87BA-B7FF9B558C78Q37469496-DA9E66DD-38AC-4FBE-81FD-A9059D3014BEQ37728495-A7530BBD-73C5-4857-B330-2CD7B494D1A5Q38344470-D0B07E0F-58B4-4891-A0C2-0D5B5BF3604CQ38649673-E38959A5-D2DF-4356-ACA5-211051DB9104Q38768833-B4A8871C-47FB-462D-AB6E-A28953F0CF57Q38892190-1B1435CE-8639-4963-AA25-E77994FD74DEQ39214035-221BF5DE-2564-4952-AD07-EDF680796223Q42357489-B4E2973B-4363-497E-9706-2B1A76675B9DQ42688550-B9A40F1A-62F0-4A3B-A31C-FA90499D37EDQ42783866-A4FAA365-BB4C-4C8B-9591-D2A59EC1CD38
P2860
Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Loss of transcription factor K ...... of human squamous cell cancer
@ast
Loss of transcription factor K ...... of human squamous cell cancer
@en
type
label
Loss of transcription factor K ...... of human squamous cell cancer
@ast
Loss of transcription factor K ...... of human squamous cell cancer
@en
prefLabel
Loss of transcription factor K ...... of human squamous cell cancer
@ast
Loss of transcription factor K ...... of human squamous cell cancer
@en
P2093
P2860
P1433
P1476
Loss of transcription factor K ...... of human squamous cell cancer
@en
P2093
Abha Goyal
Antonia R Sepulveda
Hiroshi Nakagawa
Janelle Billig
Jonathan P Katz
Marie-Pier Tetreault
Noel Victor
Yizeng Yang
P2860
P304
P356
10.1158/0008-5472.CAN-11-1702
P407
P577
2011-08-25T00:00:00Z