Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age - Wikidata - wikimedia - TriplyDB

Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age

Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age

http://www.wikidata.org/entity/Q35350491

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Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]Syndromic gastrointestinal stromal tumors Succinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and Epigenetics Rare Tumors in Children: Progress Through Collaboration Personalized Medicine in Gastrointestinal Stromal Tumor (GIST): Clinical Implications of the Somatic and Germline DNA Analysis Novel uses of immunohistochemistry in the diagnosis and classification of soft tissue tumors Connecting molecular pathways to hereditary cancer risk syndromes Molecular subtypes of gastrointestinal stromal tumors and their prognostic and therapeutic implications.Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial.The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review.Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).MDCT features of succinate dehydrogenase (SDH)-deficient gastrointestinal stromal tumours.SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors Succinate dehydrogenase (SDH)-deficient renal carcinoma: a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients.Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone.Succinate dehydrogenase-deficient gastrointestinal stromal tumors.The standard diagnosis, treatment, and follow-up of gastrointestinal stromal tumors based on guidelines A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib.Gastrointestinal stromal tumor - an evolving concept.Impact of age and gender on tumor related prognosis in gastrointestinal stromal tumors (GIST).KIT Mutation and Loss of 14q May Be Sufficient for the Development of Clinically Symptomatic Very Low-Risk GIST.KRAS and KIT Gatekeeper Mutations Confer Polyclonal Primary Imatinib Resistance in GI Stromal Tumors: Relevance of Concomitant Phosphatidylinositol 3-Kinase/AKT Dysregulation.Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor.Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 1-Common Sarcomas: From the Radiologic Pathology Archives.State of the Art in the Treatment of Gastrointestinal Stromal Tumors.A novel germline mutation in SDHA identified in a rare case of gastrointestinal stromal tumor complicated with renal cell carcinoma.Plexiform myxoid gastrointestinal stromal tumor: a potential diagnostic pitfall in pathological findings.Expression of the receptor for type i insulin-like growth factor (IGF1R) in gastrointestinal stromal tumors: an immunohistochemical study of 1078 cases with diagnostic and therapeutic implications.The genetic landscape of gastrointestinal stromal tumor lacking KIT and PDGFRA mutations.Immunohistochemical loss of succinate dehydrogenase subunit A (SDHA) in gastrointestinal stromal tumors (GISTs) signals SDHA germline mutation Gene expression identifies heterogeneity of metastatic behavior among gastrointestinal stromal tumors.Overexpression of insulin-like growth factor 1 receptor and frequent mutational inactivation of SDHA in wild-type SDHB-negative gastrointestinal stromal tumors.Extended adjuvant therapy with imatinib in patients with gastrointestinal stromal tumors : recommendations for patient selection, risk assessment, and molecular response monitoring.Plexiform fibromyxoma with cotyledon-like serosal growth: A case report of a rare gastric tumor and review of the literature.Surgical treatment of gastric gastrointestinal stromal tumor Molecular alterations and expression of succinate dehydrogenase complex in wild-type KIT/PDGFRA/BRAF gastrointestinal stromal tumors.Brunner's gland cyst in combination with gastrointestinal stromal tumor: A case report.Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors.Succinate dehydrogenase expression in breast cancer.

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P2860

Succinate dehydrogenase-deficient GISTs: a clinicopathologic, immunohistochemical, and molecular genetic study of 66 gastric GISTs with predilection to young age

http://www.wikidata.org/entity/Q35350491

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2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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Czeslaw Osuch

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Jerzy Lasota

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Maarit Sarlomo-Rikala

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Markku Miettinen

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Zeng-Feng Wang

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P2860

Low penetrance of a SDHB mutation in a large Dutch paraganglioma family

Leigh syndrome caused by mutations in the flavoprotein (Fp) subunit of succinate dehydrogenase (SDHA)

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

Immunohistochemistry for SDHB triages genetic testing of SDHB, SDHC, and SDHD in paraganglioma-pheochromocytoma syndromes

Immunohistochemistry for SDHB divides gastrointestinal stromal tumors (GISTs) into 2 distinct types

The R22X mutation of the SDHD gene in hereditary paraganglioma abolishes the enzymatic activity of complex II in the mitochondrial respiratory chain and activates the hypoxia pathway

SDHA loss-of-function mutations in KIT-PDGFRA wild-type gastrointestinal stromal tumors identified by massively parallel sequencing.

Succinate dehydrogenase - Assembly, regulation and role in human disease.

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma.

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51715658

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21997692

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