Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them
about
Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene clusterIdentification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytesFormation of genes coding for hybrid proteins by recombination between related, cloned genes in E. coliTwo distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptidesDNA sequence of a major human leukocyte interferon geneGenetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progressionInterferon induction and function at the mucosal surface.Shuffled antibody libraries created by in vivo homologous recombination and yeast surface display.Functionally diverging molecular quasi-species evolve by crossing two enzymesCross-species antiviral activity of a recombinant human alpha-interferon hybrid.Synergistic activity of combinations of recombinant human alpha interferon and acyclovir, administered concomitantly and in sequence, against a lethal herpes simplex virus type 1 infection in mice.Structure and expression of cloned murine IFN-alpha genes.Chemical synthesis of a human interferon-alpha 2 gene and its expression in Escherichia coliAntiviral activities of hybrids of two major human leukocyte interferons.Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptorBiologic activity in a fragment of recombinant human interferon alphaExpression of a chemically synthesized human alpha 1 interferon geneHigh-level expression of an interferon alpha 2 gene cloned in phage M13mp7 and subsequent purification with a monoclonal antibody.A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo.Antiviral activity of bacteria-derived human alpha interferons against encephalomyocarditis virus infection of mice.Cytokines: an overview.Generation of hybrid genes and proteins by vaccinia virus-mediated recombination: application to human immunodeficiency virus type 1 env.Antiviral and protein-inducing activities of recombinant human leukocyte interferons and their hybrids.Interferon-induced inhibition of Chlamydia trachomatis: dissociation from antiviral and antiproliferative effectsAntibodies that neutralize human beta interferon biologic activity recognize a linear epitope: analysis by synthetic peptide mapping.Constitutive production of human interferons by mouse cells with bovine papillomavirus as a vector.Orientation of a human leukocyte interferon molecule on its cell surface receptor: carboxyl terminus remains accessible to a monoclonal antibody made against a synthetic interferon fragment.From cloning to a commercial realization: human alpha interferon.Inhibition of growth, transformation, and expression of human papillomavirus type 16 E7 in human keratinocytes by alpha interferons.Interferon synthesis by micro-organisms.Efficacy of a single intravesical treatment with Ad-IFN/Syn 3 is dependent on dose and urine IFN concentration obtained: implications for clinical investigation.The construction of a synthetic Escherichia coli trp promoter and its use in the expression of a synthetic interferon gene.Single amino acid changes that render human IFN-alpha 2 biologically active on mouse cells.Characterization and expression of a murine gene homologous to human EPA/TIMP: a virus-induced gene in the mouseReceptor dynamics of closely related ligands: "fast' and "slow' interferons.Three-dimensional crystal structure of recombinant murine interferon-beta.Specific antiviral activities of the human alpha interferons are determined at the level of receptor (IFNAR) structure.Biological properties of interferon-alpha produced Ex vivo by whole blood of patients infected by human immunodeficiency virus-1.Combination therapy of colon carcinoma 26 in mice with recombinant human interleukin-2 and interferon-alpha A/D: occurrence of large granular cells in the tumor.Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis
P2860
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P2860
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them
description
1981 nî lūn-bûn
@nan
1981 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1981 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1981年の論文
@ja
1981年論文
@yue
1981年論文
@zh-hant
1981年論文
@zh-hk
1981年論文
@zh-mo
1981年論文
@zh-tw
1981年论文
@wuu
name
Target cell specificity of two ...... id molecules derived from them
@ast
Target cell specificity of two ...... id molecules derived from them
@en
type
label
Target cell specificity of two ...... id molecules derived from them
@ast
Target cell specificity of two ...... id molecules derived from them
@en
prefLabel
Target cell specificity of two ...... id molecules derived from them
@ast
Target cell specificity of two ...... id molecules derived from them
@en
P2093
P2860
P356
P1476
Target cell specificity of two ...... id molecules derived from them
@en
P2093
P2860
P304
P356
10.1073/PNAS.78.5.2848
P407
P577
1981-05-01T00:00:00Z