A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis.
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialCa(V)1.1: The atypical prototypical voltage-gated Ca²⁺ channelChannelopathies of skeletal muscle excitabilitySkeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractilityThe divergence, actions, roles, and relatives of sodium-coupled bicarbonate transportersNovel mutations in human and mouse SCN4A implicate AMPK in myotonia and periodic paralysis.Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysisGating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins.Muscle channelopathies: the nondystrophic myotonias and periodic paralyses.Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy.β-Catenin stabilization in skeletal muscles, but not in motor neurons, leads to aberrant motor innervation of the muscle during neuromuscular development in micePathophysiological role of omega pore current in channelopathiesLeaky channels make weak muscles.A calcium channel mutant mouse model of hypokalemic periodic paralysisA novel NaV1.5 voltage sensor mutation associated with severe atrial and ventricular arrhythmias.Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.Mice with an NaV1.4 sodium channel null allele have latent myasthenia, without susceptibility to periodic paralysis.Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis.Transient compartment-like syndrome and normokalaemic periodic paralysis due to a Ca(v)1.1 mutation.Advances in targeting voltage-gated sodium channels with small molecules.Biophysics, pathophysiology, and pharmacology of ion channel gating pores.Ion channel engineering: perspectives and strategies.HCO(3)(-)-independent conductance with a mutant Na(+)/HCO(3)(-) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis.Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy.Phospholemman, a major regulator of skeletal muscle Na+/K+-ATPase, is not mutated in probands with hypokalemic periodic paralysis.Atomistic Modeling of Ion Conduction through the Voltage-Sensing Domain of the Shaker K+ Ion Channel.An atypical CaV1.1 mutation reveals a common mechanism for hypokalemic periodic paralysis.Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels.Activity-induced Ca2+ signaling in perisynaptic Schwann cells of the early postnatal mouse is mediated by P2Y1 receptors and regulates muscle fatigue.Sodium Channelopathies of Skeletal Muscle.A Mixed Periodic Paralysis & Myotonia Mutant, P1158S, Imparts pH-Sensitivity in Skeletal Muscle Voltage-gated Sodium Channels.Gating Pore Currents in Sodium ChannelsA leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy
P2860
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P2860
A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@ast
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@en
type
label
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@ast
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@en
prefLabel
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@ast
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@en
P2093
P2860
P356
P1476
A sodium channel knockin mutan ...... ypokalemic periodic paralysis.
@en
P2093
Arie F Struyk
Dennis K Burns
Hillery F Gray
Stephen C Cannon
P2860
P304
P356
10.1172/JCI57398
P407
P577
2011-09-01T00:00:00Z