TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer - Wikidata - wikimedia - TriplyDB

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

http://www.wikidata.org/entity/Q35370365

about

Integrated DNA Copy Number and Gene Expression Regulatory Network Analysis of Non-small Cell Lung Cancer Metastasis Autosomal-recessive SASH1 variants associated with a new genodermatosis with pigmentation defects, palmoplantar keratoderma and skin carcinoma.miR-146a enhances the oncogenicity of oral carcinoma by concomitant targeting of the IRAK1, TRAF6 and NUMB genes.Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity.TRAF2 is an NF-κB-activating oncogene in epithelial cancers.In silico investigation of potential TRAF6 inhibitor from traditional Chinese medicine against cancers.EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis.HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.A systematic review of microRNA expression profiling studies in human gastric cancer.A categorical network approach for discovering differentially expressed regulations in cancer.Inhibition of IRAK1/4 sensitizes T cell acute lymphoblastic leukemia to chemotherapies.Comprehensive Evaluation of Nuclear Factor-κΒ Expression Patterns in Non-Small Cell Lung Cancer.MUC1-C activates the TAK1 inflammatory pathway in colon cancer Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1.Relationship between TRAF6 and deterioration of HCC: an immunohistochemical and in vitro study.miR-146b-5p functions as a tumor suppressor by targeting TRAF6 and predicts the prognosis of human gliomas.Expression and Clinical Significance of Tumor Necrosis Factor Receptor-Associated Factor 6 in Patients With Colon Cancer siRNA-induced TRAF6 knockdown promotes the apoptosis and inhibits the invasion of human lung cancer SPC-A1 cells.Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer.Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9 TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin.TRAF molecules in cell signaling and in human diseases Mutational analysis of Polycomb genes in solid tumours identifies PHC3 amplification as a possible cancer-driving genetic alteration MyD88 and its divergent toll in carcinogenesis.Loss of connectivity in cancer co-expression networks.Role of CYB5A in pancreatic cancer prognosis and autophagy modulation K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells.Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity.Synergisic effect of APRIL knockdown and Jiedu Xiaozheng Yin, a Chinese medicinal recipe, on the inhibition of hepatocellular carcinoma cell proliferation.Dysregulation of signaling pathways associated with innate antibacterial immunity in patients with pancreatic cancer.p62: a versatile multitasker takes on cancer.Regulated intramembrane proteolysis of the TGFβ type I receptor conveys oncogenic signals.Exome sequencing of oral squamous cell carcinoma in users of Arabian snuff reveals novel candidates for driver genes.Protein-protein interaction analysis of distinct molecular pathways in two subtypes of colorectal carcinoma Computational genomic analysis of PARK7 interactome reveals high BBS1 gene expression as a prognostic factor favoring survival in malignant pleural mesothelioma.TRAF6 is required for BLyS-mediated NF-κB signaling in multiple myeloma cells.BRAF-induced tumorigenesis is IKKα-dependent but NF-κB-independent.p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.

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P2860

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

http://www.wikidata.org/entity/Q35370365

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@ast

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@en

type

label

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@ast

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@en

prefLabel

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@ast

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@en

P1433

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P1433

Journal of Clinical Investigation

P1476

TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer

@en

P2093

Adi F Gazdar

http://www.w3.org/2001/XMLSchema#string

Aly Karsan

http://www.w3.org/2001/XMLSchema#string

Daniel T Starczynowski

http://www.w3.org/2001/XMLSchema#string

Joanna Wegrzyn

http://www.w3.org/2001/XMLSchema#string

Megan Fuller

http://www.w3.org/2001/XMLSchema#string

Raj Chari

http://www.w3.org/2001/XMLSchema#string

Sophie Deléhouzée

http://www.w3.org/2001/XMLSchema#string

Stephen Lam

http://www.w3.org/2001/XMLSchema#string

Wan L Lam

http://www.w3.org/2001/XMLSchema#string

William W Lockwood

http://www.w3.org/2001/XMLSchema#string

P2860

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

Characterizing the cancer genome in lung adenocarcinoma.

Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

Identification of the familial cylindromatosis tumour-suppressor gene

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

The landscape of somatic copy-number alteration across human cancers.

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

P304

4095-4105

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P31

scholarly article

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10.1172/JCI58818

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P433

10

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P478

121

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Ming-Sound Tsao

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2011-09-12T00:00:00Z

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51632163

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21911935

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P932

3195480

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