Extrasynaptic N-methyl-D-aspartate (NMDA) receptor stimulation induces cytoplasmic translocation of the CDKL5 kinase and its proteasomal degradation.
about
What we know and would like to know about CDKL5 and its involvement in epileptic encephalopathyMolecular and genetic insights into an infantile epileptic encephalopathy - CDKL5 disorder.GluD1 is a common altered player in neuronal differentiation from both MECP2-mutated and CDKL5-mutated iPS cells.Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5CDKL5 and Shootin1 Interact and Concur in Regulating Neuronal Polarization.The neurobiology of X-linked intellectual disability.CDKL5 localizes at the centrosome and midbody and is required for faithful cell division.The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex.CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.
P2860
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P2860
Extrasynaptic N-methyl-D-aspartate (NMDA) receptor stimulation induces cytoplasmic translocation of the CDKL5 kinase and its proteasomal degradation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@ast
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@en
type
label
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@ast
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@en
prefLabel
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@ast
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@en
P2093
P2860
P356
P1476
Extrasynaptic N-methyl-D-aspar ...... d its proteasomal degradation.
@en
P2093
Charlotte Kilstrup-Nielsen
Laura Rusconi
Nicoletta Landsberger
P2860
P304
36550-36558
P356
10.1074/JBC.M111.235630
P407
P577
2011-08-05T00:00:00Z