A novel tricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor, GRL-0739, effectively inhibits the replication of multidrug-resistant HIV-1 variants and has a desirable central nervous system penetration property in vitro.
about
A Modified P1 Moiety Enhances in vitro Antiviral Activity against Various Multi-Drug-Resistant HIV-1 Variants and in vitro CNS Penetration Properties of a Novel Nonpeptidic Protease Inhibitor, GRL-10413GRL-09510, a Unique P2-Crown-Tetrahydrofuranylurethane -Containing HIV-1 Protease Inhibitor, Maintains Its Favorable Antiviral Activity against Highly-Drug-Resistant HIV-1 Variants in vitro.HIV-Associated Neurocognitive Disorder (HAND) and the Prospect of Brain-Penetrating Protease Inhibitors for Antiretroviral Treatment.
P2860
A novel tricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor, GRL-0739, effectively inhibits the replication of multidrug-resistant HIV-1 variants and has a desirable central nervous system penetration property in vitro.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A novel tricyclic ligand-conta ...... penetration property in vitro.
@ast
A novel tricyclic ligand-conta ...... penetration property in vitro.
@en
type
label
A novel tricyclic ligand-conta ...... penetration property in vitro.
@ast
A novel tricyclic ligand-conta ...... penetration property in vitro.
@en
prefLabel
A novel tricyclic ligand-conta ...... penetration property in vitro.
@ast
A novel tricyclic ligand-conta ...... penetration property in vitro.
@en
P2093
P2860
P356
P1476
A novel tricyclic ligand-conta ...... penetration property in vitro
@en
P2093
Arun K Ghosh
Debananda Das
Garth L Parham
Hiroaki Mitsuya
Pedro Miguel Salcedo-Gómez
Yasushi Tojo
P2860
P304
P356
10.1128/AAC.04757-14
P407
P577
2015-02-17T00:00:00Z