Editing of errors in selection of amino acids for protein synthesis
about
The renaissance of aminoacyl-tRNA synthesisPost-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetaseMass spectrometrical analysis of recombinant human growth hormone (Genotropin(R)) reveals amino acid substitutions in 2% of the expressed proteinEvolution of phage with chemically ambiguous proteomesIn silico discovery of aminoacyl-tRNA synthetase inhibitorsThe 2 Å crystal structure of leucyl-tRNA synthetase and its complex with a leucyl-adenylate analogueMechanistic insights into cognate substrate discrimination during proofreading in translationTrans-editing of mischarged tRNAs.p23H implicated as cis/trans regulator of AlaXp-directed editing for mammalian cell homeostasisDiscovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein TranslationIn vitro incorporation of nonnatural amino acids into protein using tRNA(Cys)-derived opal, ochre, and amber suppressor tRNAsHow translational accuracy influences reading frame maintenancetRNA-dependent pre-transfer editing by prokaryotic leucyl-tRNA synthetase.Breaking sieve for steric exclusion of a noncognate amino acid from active site of a tRNA synthetase.Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase (thr1Delta) mutantsTransfer RNA determinants for translational editing by Escherichia coli valyl-tRNA synthetaseBlocking site-to-site translocation of a misactivated amino acid by mutation of a class I tRNA synthetaseLow level genome mistranslations deregulate the transcriptome and translatome and generate proteotoxic stress in yeast.Tryptophanyl-tRNA synthetase Urzyme: a model to recapitulate molecular evolution and investigate intramolecular complementationFunctional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase.Elucidation of tRNA-dependent editing by a class II tRNA synthetase and significance for cell viabilityAn assessment of mechanisms underlying peripheral axonal degeneration caused by aminoacyl-tRNA synthetase mutations.Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy.Synthesis of cysteine-containing dipeptides by aminoacyl-tRNA synthetases.The EntF and EntE adenylation domains of Escherichia coli enterobactin synthetase: sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates.Mistranslation and its control by tRNA synthetases.Hydrolytic editing by a class II aminoacyl-tRNA synthetase.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS responseSubstrate specificity of bacterial prolyl-tRNA synthetase editing domain is controlled by a tunable hydrophobic pocketTransfer RNA-dependent cognate amino acid recognition by an aminoacyl-tRNA synthetaseRole of coupled dynamics in the catalytic activity of prokaryotic-like prolyl-tRNA synthetases.Crystallization of leucyl-tRNA synthetase complexed with tRNALeu from the archaeon Pyrococcus horikoshii.Specificity in molecular design: a physical framework for probing the determinants of binding specificity and promiscuity in a biological environment.In vitro assays for the determination of aminoacyl-tRNA synthetase editing activity.Crucial role of the C-terminal domain of Mycobacterium tuberculosis leucyl-tRNA synthetase in aminoacylation and editing.The crystal structure of yeast mitochondrial ThrRS in complex with the canonical threonine tRNA.A freestanding proofreading domain is required for protein synthesis quality control in Archaea.Aminoacyl-tRNA substrate and enzyme backbone atoms contribute to translational quality control by YbaKThe relationship between synthetic and editing functions of the active site of an aminoacyl-tRNA synthetase
P2860
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P2860
Editing of errors in selection of amino acids for protein synthesis
description
1992 nî lūn-bûn
@nan
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Editing of errors in selection of amino acids for protein synthesis
@ast
Editing of errors in selection of amino acids for protein synthesis
@en
type
label
Editing of errors in selection of amino acids for protein synthesis
@ast
Editing of errors in selection of amino acids for protein synthesis
@en
prefLabel
Editing of errors in selection of amino acids for protein synthesis
@ast
Editing of errors in selection of amino acids for protein synthesis
@en
P2860
P1476
Editing of errors in selection of amino acids for protein synthesis
@en
P2093
H Jakubowski
P2860
P304
P577
1992-09-01T00:00:00Z