FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection - Wikidata - wikimedia - TriplyDB

FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection

FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection

http://www.wikidata.org/entity/Q35404705

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Diametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunology From genetics of inflammatory bowel disease towards mechanistic insights Therapeutic approaches for celiac disease Review of statistical methodologies for the detection of parent-of-origin effects in family trio genome-wide association data with binary disease traits.Immune and genetic gardening of the intestinal microbiome.Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets.Glucocorticoids and microbiota regulate ontogeny of intestinal fucosyltransferase 2 requisite for gut homeostasis.Faecal microbiota composition in adults is associated with the FUT2 gene determining the secretor status.Innate lymphoid cells regulate intestinal epithelial cell glycosylation FUT2 nonfunctional variant: a "missing link" between genes and environment in type 1 diabetes?Maternal fucosyltransferase 2 status affects the gut bifidobacterial communities of breastfed infants Intestinal fucose as a mediator of host-microbe symbiosis.Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection Secretor Status Is Strongly Associated with Microbial Alterations Observed during Pregnancy.Association of Ulcerative Colitis with FUT2 and FUT3 Polymorphisms in Patients from Southeast China ABO antigen and secretor statuses are not associated with gut microbiota composition in 1,500 twins Metagenomics and personalized medicine.IL-10-producing CD4(+) T cells negatively regulate fucosylation of epithelial cells in the gut Association of cardiovascular and metabolic disease genes with psoriasis Mothers Secretor Status Affects Development of Childrens Microbiota Composition and Function: A Pilot Study.Intestinal epithelial cells as mediators of the commensal-host immune crosstalk.2'-fucosyllactose: an abundant, genetically determined soluble glycan present in human milk.Molecular mechanisms in autoimmune type 1 diabetes: a critical review.The human milk oligosaccharide 2'-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation.Identification of novel risk genes associated with type 1 diabetes mellitus using a genome-wide gene-based association analysis.Blood type biochemistry and human disease.Epithelial glycosylation in gut homeostasis and inflammation.FUT2: filling the gap between genes and environment in Behçet's disease?FUT2 genetic variants as predictors of tumor development with hepatocellular carcinoma.Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections.Association of Fucosyltransferase 2 Gene Polymorphisms with Inflammatory Bowel Disease in Patients from Southeast China Human genetic variation and the gut microbiome in disease.Human microbiota, blood group antigens, and disease.FUT2 non-secretor status is associated with Type 1 diabetes susceptibility in Japanese children.An update on vitamin B12-related gene polymorphisms and B12 status.Characterisation of rapid progressors to type 1 diabetes among children with HLA-conferred disease susceptibility.Application study of 1,2-α-l-fucosynthase: introduction of Fucα1-2Gal disaccharide structures on N-glycan, ganglioside, and xyloglucan oligosaccharide.Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study.Introduction of H-antigens into oligosaccharides and sugar chains of glycoproteins using highly efficient 1,2-α-l-fucosynthase.

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FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection

http://www.wikidata.org/entity/Q35404705

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2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection

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Helen Stevens

http://www.w3.org/2001/XMLSchema#string

Jason D Cooper

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Kate Downes

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Pamela Clarke

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Trupti Mistry

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P2860

The G428A nonsense mutation in FUT2 provides strong but not absolute protection against symptomatic GII.4 Norovirus infection

A homozygous nonsense mutation (428G-->A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Shared and distinct genetic variants in type 1 diabetes and celiac disease

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

Human susceptibility and resistance to Norwalk virus infection

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease

Population structure, differential bias and genomic control in a large-scale, case-control association study

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3081-3084

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10.2337/DB11-0638

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11

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60

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51743862

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22025780

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type-1 diabetes

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3198057

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