Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species. - Wikidata - wikimedia - TriplyDB

Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species.

Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species.

http://www.wikidata.org/entity/Q35424191

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Redox Modulating NRF2: A Potential Mediator of Cancer Stem Cell Resistance Anti-inflammatory/antioxidant use in long-term maintenance cancer therapy: a new therapeutic approach to disease progression and recurrence Chemotherapy targeting cancer stem cells Docetaxel-induced polyploidization may underlie chemoresistance and disease relapse ERO1α-dependent endoplasmic reticulum-mitochondrial calcium flux contributes to ER stress and mitochondrial permeabilization by procaspase-activating compound-1 (PAC-1).Chronic oxidative stress increases growth and tumorigenic potential of MCF-7 breast cancer cells.Circulating Tumor Cells in Early-Stage Breast Cancer.C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy.Chemotherapeutics-induced Oct4 expression contributes to drug resistance and tumor recurrence in bladder cancer.Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs.Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3.Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells.Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations.Polyploidy Formation in Doxorubicin-Treated Cancer Cells Can Favor Escape from Senescence.Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells.A multi-stage process including transient polyploidization and EMT precedes the emergence of chemoresistent ovarian carcinoma cells with a dedifferentiated and pro-inflammatory secretory phenotype Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.Repopulation of ovarian cancer cells after chemotherapy Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment.The autophagy inhibitor chloroquine targets cancer stem cells in triple negative breast cancer by inducing mitochondrial damage and impairing DNA break repair.Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells Is it time for a new paradigm for systemic cancer treatment? Lessons from a century of cancer chemotherapy Reactive oxygen species in eradicating acute myeloid leukemic stem cells Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal.Involvement of NRF2 Signaling in Doxorubicin Resistance of Cancer Stem Cell-Enriched Colonospheres.Low-dose triptolide in combination with idarubicin induces apoptosis in AML leukemic stem-like KG1a cell line by modulation of the intrinsic and extrinsic factors.Another facet to the anticancer response to lamellarin D: induction of cellular senescence through inhibition of topoisomerase I and intracellular Ros production Pregnane X-receptor promotes stem cell-mediated colon cancer relapse The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration.Mitotic catastrophe and cell cycle arrest are alternative cell death pathways executed by bortezomib in rituximab resistant B-cell lymphoma cells Metabolic enzymes: key modulators of functionality in cancer stem-like cells.Chemotherapy enriches for an invasive triple-negative breast tumor cell subpopulation expressing a precursor form of N-cadherin on the cell surface.In vitro long-term treatment with MAPK inhibitors induces melanoma cells with resistance plasticity to inhibitors while retaining sensitivity to CD8 T cells.A nucleolytic lupus autoantibody is toxic to BRCA2-deficient cancer cells.MicroRNAs regulate both epithelial-to-mesenchymal transition and cancer stem cells.Constitutive expression and activation of stress response genes in cancer stem-like cells/tumour initiating cells: potent targets for cancer stem cell therapy.EZH2 inhibition re-sensitizes multidrug resistant B-cell lymphomas to etoposide mediated apoptosis.Modulation of SOX2 expression delineates an end-point for paclitaxel-effectiveness in breast cancer stem cells.Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work?

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Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen species.

http://www.wikidata.org/entity/Q35424191

description

2011 nî lūn-bûn

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2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Drug-induced senescence genera ...... h low reactive oxygen species.

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Drug-induced senescence genera ...... h low reactive oxygen species.

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type

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Drug-induced senescence genera ...... h low reactive oxygen species.

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Drug-induced senescence genera ...... h low reactive oxygen species.

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Drug-induced senescence genera ...... h low reactive oxygen species.

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Drug-induced senescence genera ...... h low reactive oxygen species.

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Drug-induced senescence genera ...... h low reactive oxygen species.

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P2093

Jem Prabhakar

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M Radhakrishna Pillai

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S Asha Nair

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Santhi Achuthan

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Thankayyan R Santhoshkumar

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P2860

WWP2 promotes degradation of transcription factor OCT4 in human embryonic stem cells

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

Prospective identification of tumorigenic breast cancer cells

High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening

Specific association of human telomerase activity with immortal cells and cancer

Identification of human brain tumour initiating cells

Identification and expansion of the tumorigenic lung cancer stem cell population

Linking functional decline of telomeres, mitochondria and stem cells during ageing

Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells

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10.1074/JBC.M110.200675

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