Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine
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Alcohol, aldehydes, adducts and airwaysMass spectrometry for the assessment of the occurrence and biological consequences of DNA adductsA chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivoImpairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion.Evolution of research on the DNA adduct chemistry of N-nitrosopyrrolidine and related aldehydes.Detection of 7-(2'-carboxyethyl)guanine but not 7-carboxymethylguanine in human liver DNA.Kinetics of DNA adduct formation in the oral cavity after drinking alcohol.Time course of DNA adduct formation in peripheral blood granulocytes and lymphocytes after drinking alcohol.Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.Quantitation of DNA adducts by stable isotope dilution mass spectrometry.Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues with abasic sites in duplex DNAAlcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain.Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.Update on pancreatic cancer and alcohol-associated risk.Biomarkers of exposure and effect in human lymphoblastoid TK6 cells following [13C2]-acetaldehyde exposure.Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometryQuantitation of an acetaldehyde adduct in human leukocyte DNA and the effect of smoking cessation.Investigation of the reaction of myosmine with sodium nitrite in vitro and in rats.Analysis of pyridyloxobutyl DNA adducts in F344 rats chronically treated with (R)- and (S)-N'-nitrosonornicotineAnalysis of adducts in hepatic DNA of rats treated with N-nitrosopyrrolidine.Detection and quantitation of acrolein-derived 1,N2-propanodeoxyguanosine adducts in human lung by liquid chromatography-electrospray ionization-tandem mass spectrometry.Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanolDNA damage and neurotoxicity of chronic alcohol abuseMass spectrometry of structurally modified DNA.Analysis of crotonaldehyde- and acetaldehyde-derived 1,n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry.Differential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerasesAnalysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine.Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Analysis of O(6)-[4-(3-Pyridyl)-4-oxobut-1-yl]-2'-deoxyguanosine and Other DNA Adducts in Rats Treated with Enantiomeric or Racemic N'-Nitrosonornicotine.Application of a high-resolution mass-spectrometry-based DNA adductomics approach for identification of DNA adducts in complex mixtures.Vinyl acetate monomer (VAM) genotoxicity profile: relevance for carcinogenicity.Acetaldehyde and the genome: beyond nuclear DNA adducts and carcinogenesis.Alcohol and head and neck cancer.Analysis of 4-hydroxy-1-(3-pyridyl)-1-butanone (HPB)-releasing DNA adducts in human exfoliated oral mucosa cells by liquid chromatography-electrospray ionization-tandem mass spectrometryIncreased levels of the acetaldehyde-derived DNA adduct N 2-ethyldeoxyguanosine in oral mucosa DNA from Rhesus monkeys exposed to alcohol.Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples.
P2860
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P2860
Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@ast
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@en
type
label
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@ast
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@en
prefLabel
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@ast
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@en
P2093
P2860
P356
P1476
Identification of an acetaldeh ...... tion as N2-ethyldeoxyguanosine
@en
P2093
J Bradley Hochalter
Mingyao Wang
Nanxiong Yu
Peter W Villalta
Stephen S Hecht
P2860
P304
P356
10.1021/TX0502948
P577
2006-02-01T00:00:00Z