Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway - Wikidata - wikimedia - TriplyDB

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway

http://www.wikidata.org/entity/Q35458516

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S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3 Mevalonate cascade regulation of airway mesenchymal cell autophagy and apoptosis: a dual role for p53 In Vitro Antioxidant versus Metal Ion Chelating Properties of Flavonoids: A Structure-Activity Investigation Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications Cancer stem cells as targets for cancer therapy: selected cancers as examples.Tolerance of fungal infection in European water frogs exposed to Batrachochytrium dendrobatidis after experimental reduction of innate immune defenses.Apoptosis-inducing factor: structure, function, and redox regulation.The cladribine conundrum: deciphering the drug's mechanism of action.The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis.Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death Evaluation of Antimicrobial and Healing Activities of Frog Skin on Guinea Pigs Wounds.Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor.On the physiology and pathophysiology of antimicrobial peptides.A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer.Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.Regulation of autophagy in hematological malignancies: role of reactive oxygen species.The autophagic paradox in cancer therapy.Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development.Nanoparticle-conjugated animal venom-toxins and their possible therapeutic potential.Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides.Mechanisms of autophagy and apoptosis: Recent developments in breast cancer cells.Convergent evolution of defensin sequence, structure and function.Novel pathogenesis: regulation of apoptosis by Apelin/APJ system.Antimicrobial peptides with selective antitumor mechanisms: prospect for anticancer applications.Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity.Lysosomal localization and mechanism of membrane penetration influence nonenveloped virus activation of the NLRP3 inflammasome.Adenovirus membrane penetration activates the NLRP3 inflammasome.AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells.Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway.Inhibition of ERK attenuates autophagy and potentiates tumour necrosis factor-alpha-induced cell death in MCF-7 cells Altered α-defensin 5 expression in cervical squamocolumnar junction: implication in the formation of a viral/tumour-permissive microenvironment.Mitoptosis, a novel mitochondrial death mechanism leading predominantly to activation of autophagy.Targeting metabolism and autophagy in the context of haematologic malignancies Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae.Molecular cloning and expression of ranalexin, a bioactive antimicrobial peptide from Rana catesbeiana in Escherichia coli and assessments of its biological activities.Purification and modeling amphipathic alpha helical antimicrobial peptides from skin secretions of Euphlyctis cyanophlyctis.Antioxidant properties of a human neuropeptide and its protective effect on free radical-induced DNA damage.Identification and characterization of two novel antimicrobial peptides, temporin-Ra and temporin-Rb, from skin secretions of the marsh frog (Rana ridibunda).Human β-defensins and psoriasin/S100A7 expression in salivary glands: anti-oncogenic molecules for potential therapeutic approaches.Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cells

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P2860

Brevinin-2R(1) semi-selectively kills cancer cells by a distinct mechanism, which involves the lysosomal-mitochondrial death pathway

http://www.wikidata.org/entity/Q35458516

description

2008 nî lūn-bûn

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2008 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2008 թվականի հունիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Brevinin-2R(1) semi-selectivel ...... al-mitochondrial death pathway

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Brevinin-2R(1) semi-selectivel ...... al-mitochondrial death pathway

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Brevinin-2R(1) semi-selectivel ...... al-mitochondrial death pathway

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Brevinin-2R(1) semi-selectivel ...... al-mitochondrial death pathway

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J.1582-4934.2008.00129.X

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Journal of Cellular and Molecular Medicine

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Brevinin-2R(1) semi-selectivel ...... al-mitochondrial death pathway

@en

P2093

Andrew J Halayko

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Evan P Booy

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Hossein Naderi-Manesh

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Kamran Kadkhoda

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Saeid Ghavami

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Tadeusz J Kroczak

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Thomas Klonisch

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P2860

Two distinct pathways leading to nuclear apoptosis

BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites

Endonuclease G is an apoptotic DNase when released from mitochondria

Programmed death phenomena: from organelle to organism

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

Ion channels and bacterial infection: the case of beta-barrel pore-forming protein toxins of Staphylococcus aureus.

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor.

Antimicrobial peptides derived from pepsinogens in the stomach of the bullfrog, Rana catesbeiana.

Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy.

A family of brevinin-2 peptides with potent activity against Pseudomonas aeruginosa from the skin of the Hokkaido frog, Rana pirica.

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1005-1022

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scholarly article

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10.1111/J.1582-4934.2008.00129.X

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3

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12

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Spencer B. Gibson

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2008-06-01T00:00:00Z

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5355270

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18494941

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4401144

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