β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.
about
Pharmacological Targeting of the Hepcidin/Ferroportin AxisIron, anemia and hepcidin in malariaIneffective erythropoiesis in β -thalassemiaCancer cells with irons in the fireβ-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapiesReciprocal regulation of γ-globin expression by exo-miRNAs: Relevance to γ-globin silencing in β-thalassemia major.β-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis.A phase 1 study of ACE-536, a regulator of erythroid differentiation, in healthy volunteers.Hepcidin expression in iron overload diseases is variably modulated by circulating factorsStatus of Superoxide Dismutase in Transfusion Dependent Thalassaemia.Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia.A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors.Abnormal erythroid maturation leads to microcytic anemia in the TSAP6/Steap3 null mouse modelAltered erythropoiesis and iron metabolism in carriers of thalassemiaReversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.3,1-Benzothiazines, 1,4-Benzodioxines and 1,4-Benzoxazines as Inhibitors of Matriptase-2: Outcome of a Focused Screening Approach.Deletion of TMPRSS6 attenuates the phenotype in a mouse model of β-thalassemia.Hepcidin/Ferritin Quotient Helps to Predict Spontaneous Recovery from Iron Loss following Blood Donation.Model-Based Optimisation of Deferoxamine Chelation Therapy.Pathophysiology and Clinical Manifestations of the β-Thalassemias.Erythropoietic drive is the strongest predictor of hepcidin level in adults with sickle cell diseasePomalidomide reverses γ-globin silencing through the transcriptional reprogramming of adult hematopoietic progenitorsCorrelation of BACH1 and Hemoglobin E/Beta-Thalassemia Globin Expression.Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.Striking the target in iron overload disorders.Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemiaAn RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia.The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice.Differential effects of the type of iron chelator on the absolute number of hematopoietic peripheral progenitors in patients with β-thalassemia majorNon-transfusion-dependent thalassemias.Gene therapy for hemoglobinopathies: progress and challenges.Regulation of erythropoiesis by hypoxia-inducible factorsThe gut in iron homeostasis: role of HIF-2 under normal and pathological conditionsIntestinal HIF2α promotes tissue-iron accumulation in disorders of iron overload with anemia.Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice.Modulators of erythropoiesis: emerging therapies for hemoglobinopathies and disorders of red cell production.The role of ineffective erythropoiesis in non-transfusion-dependent thalassemia.The regulation of iron transport.Management of non-transfusion-dependent thalassemia: a practical guide.Iron age: novel targets for iron overload.
P2860
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P2860
β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@ast
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@en
type
label
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@ast
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@en
prefLabel
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@ast
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@en
P2860
P1433
P1476
β-thalassemia: a model for elu ...... ropoiesis and iron metabolism.
@en
P2093
Stefano Rivella
Yelena Ginzburg
P2860
P304
P356
10.1182/BLOOD-2011-03-283614
P407
P577
2011-07-18T00:00:00Z