Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis. - Wikidata - wikimedia - TriplyDB

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

http://www.wikidata.org/entity/Q35489713

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Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages A highly conserved mycobacterial cholesterol catabolic pathway Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity A novel role of the PrpR as a transcription factor involved in the regulation of methylcitrate pathway in Mycobacterium tuberculosis Substrate uptake and subcellular compartmentation of anoxic cholesterol catabolism in Sterolibacterium denitrificans Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?Catabolism and biotechnological applications of cholesterol degrading bacteria.RNA Profiling Analysis of the Serum Exosomes Derived from Patients with Active and Latent Mycobacterium tuberculosis Infection Microbial steroid transformations: current state and prospects.Mycobacterium tuberculosis cholesterol catabolism requires a new class of acyl coenzyme A dehydrogenase.The CYP7A1 gene rs3808607 variant is associated with susceptibility of tuberculosis in Moroccan population.Cholesterol ester oxidation by mycobacterial cytochrome P450.Quantitative mass spectrometry reveals plasticity of metabolic networks in Mycobacterium smegmatis.Transcription of genes involved in sulfolipid and polyacyltrehalose biosynthesis of Mycobacterium tuberculosis in experimental latent tuberculosis infection.FadA5 a thiolase from Mycobacterium tuberculosis: a steroid-binding pocket reveals the potential for drug development against tuberculosis Cholesterol oxidase is indispensable in the pathogenesis of Mycobacterium tuberculosis Comprehensive insights into transcriptional adaptation of intracellular mycobacteria by microbe-enriched dual RNA sequencing Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells.Homologues of xenobiotic metabolizing N-acetyltransferases in plant-associated fungi: Novel functions for an old enzyme family.Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1.Heme and I.Detection of a Putative TetR-Like Gene Related to Mycobacterium bovis BCG Growth in Cholesterol Using a gfp-Transposon Mutagenesis System.Cytochrome P450 125A4, the Third Cholesterol C-26 Hydroxylase from Mycobacterium smegmatis Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism Cholesterol Analogs with Degradation-resistant Alkyl Side Chains Are Effective Mycobacterium tuberculosis Growth Inhibitors.RNA-Seq analysis uncovers non-coding small RNA system of Mycobacterium neoaurum in the metabolism of sterols to accumulate steroid intermediates.Plasma Membrane Profiling Reveals Upregulation of ABCA1 by Infected Macrophages Leading to Restriction of Mycobacterial Growth.The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage.Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other Bacteria.Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling.The multiple stress responsive transcriptional regulator Rv3334 of Mycobacterium tuberculosis is an autorepressor and a positive regulator of kstR.Cholesterol metabolism: a potential therapeutic target in Mycobacteria.PCSK9 at the crossroad of cholesterol metabolism and immune function during infections.The Goldilocks model of immune symbiosis with Mycobacteria and Candida colonizers.The Role of fadD19 and echA19 in Sterol Side Chain Degradation by Mycobacterium smegmatis.Global adaptation to a lipid environment triggers the dormancy-related phenotype of Mycobacterium tuberculosis.Potential effect of ezetimibe against Mycobacterium tuberculosis infection in type II diabetes.Roles of the Mevalonate Pathway and Cholesterol Trafficking in Pulmonary Host Defense.Lack of cross-protection against Mycoplasma haemofelis infection and signs of enhancement in "Candidatus Mycoplasma turicensis"-recovered cats.

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P2860

Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

http://www.wikidata.org/entity/Q35489713

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

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Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

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Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

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J.TIM.2011.07.009

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Trends in Microbiology

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Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.

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Hugues Ouellet

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Jonathan B Johnston

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Paul R Ortiz de Montellano

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P2860

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one

A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism

Biochemical differentiation of Mycobacterium tuberculosis grown in vivo and in vitro

Phylogenetic and biochemical evidence for sterol synthesis in the bacterium Gemmata obscuriglobus

Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids

The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection

Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis

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10.1016/J.TIM.2011.07.009

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Mycobacterium tuberculosis

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