Diabetes and insulin in regulation of brain cholesterol metabolism
about
Complex mechanisms linking neurocognitive dysfunction to insulin resistance and other metabolic dysfunctionDifferential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistanceTissue cholesterol content alterations in streptozotocin-induced diabetic rats.Insulin action in brain regulates systemic metabolism and brain function.Brain aging and AD-like pathology in streptozotocin-induced diabetic rats.Reduction of the cholesterol sensor SCAP in the brains of mice causes impaired synaptic transmission and altered cognitive function.Differential effects of angiopoietin-like 4 in brain and muscle on regulation of lipoprotein lipase activityHMG-CoA Reductase Inhibitors Bind to PPARα to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice.Downregulation of cholesterol biosynthesis genes in the forebrain of ERCC1-deficient miceA comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma.Constitutive cholesterol-dependent endocytosis of melanocortin-4 receptor (MC4R) is essential to maintain receptor responsiveness to α-melanocyte-stimulating hormone (α-MSH).Effect of cholesterol reduction on receptor signaling in neurons.Unraveling the Paradox of Selective Insulin Resistance in the Liver: the Brain-Liver ConnectionHepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6Leptin regulation of Hsp60 impacts hypothalamic insulin signalingRNA-seq analysis of the hypothalamic transcriptome reveals the networks regulating physiopathological progress in the diabetic GK rat.Misregulation of an adaptive metabolic response contributes to the age-related disruption of lipid homeostasis in Drosophila.Promoting longevity by maintaining metabolic and proliferative homeostasisHigh glucose upregulates BACE1-mediated Aβ production through ROS-dependent HIF-1α and LXRα/ABCA1-regulated lipid raft reorganization in SK-N-MC cells.Mild lipid stress induces profound loss of MC4R protein abundance and function.Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statinsDopamine Adaptations as a Common Pathway for Neurocognitive Impairment in Diabetes and Obesity: A Neuropsychological Perspective.SREBPs: metabolic integrators in physiology and metabolism.A pathway approach to investigate the function and regulation of SREBPs.Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.MicroRNAs in metabolism.Harnessing the trophic and modulatory potential of statins in a dopaminergic cell line.The interplay between cell signalling and the mevalonate pathway in cancer.Role of leptin on the expression of low density lipoprotein receptor.Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism.NCEH-1 modulates cholesterol metabolism and protects against α-synuclein toxicity in a C. elegans model of Parkinson's disease.A Prospective Birth Cohort Study on Maternal Cholesterol Levels and Offspring Attention Deficit Hyperactivity Disorder: New Insight on Sex Differences.Matrix metalloproteinase 14 modulates diabetes and Alzheimer's disease cross-talk: a meta-analysis.Hypocholesterolemia is an independent risk factor for depression disorder and suicide attempt in Northern Mexican population.SREBP-regulated lipid metabolism: convergent physiology - divergent pathophysiology.Diabetes-induced impairments of the exocytosis process and the effect of gabapentin: the link with cholesterol level in neuronal plasma membranes.Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation.A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin.Histone deacetylase inhibitor, trichostatin A, improves learning and memory in high-fat diet-induced cognitive deficits in mice.Insulin regulates astrocyte gliotransmission and modulates behavior.
P2860
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P2860
Diabetes and insulin in regulation of brain cholesterol metabolism
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Diabetes and insulin in regulation of brain cholesterol metabolism
@ast
Diabetes and insulin in regulation of brain cholesterol metabolism
@en
type
label
Diabetes and insulin in regulation of brain cholesterol metabolism
@ast
Diabetes and insulin in regulation of brain cholesterol metabolism
@en
prefLabel
Diabetes and insulin in regulation of brain cholesterol metabolism
@ast
Diabetes and insulin in regulation of brain cholesterol metabolism
@en
P2093
P2860
P1433
P1476
Diabetes and insulin in regulation of brain cholesterol metabolism
@en
P2093
Enxuan Jing
Jeffrey G McDonald
Ryo Suzuki
Sudha B Biddinger
Suzanne Craft
Thomas J Montine
P2860
P304
P356
10.1016/J.CMET.2010.11.006
P577
2010-12-01T00:00:00Z