TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer - Wikidata - wikimedia - TriplyDB

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer

http://www.wikidata.org/entity/Q35501271

about

c-Rel and its many roles in cancer: an old story with new twists Anti-Tumor Immunity in Head and Neck Cancer: Understanding the Evidence, How Tumors Escape and Immunotherapeutic Approaches Caught in the cross fire: p53 in inflammation.The p53 circuit board On Predicting lung cancer subtypes using 'omic' data from tumor and tumor-adjacent histologically-normal tissue.Interplay between ΔNp63 and miR-138-5p regulates growth, metastasis and stemness of oral squamous cell carcinoma Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin Roles of tumor suppressors in regulating tumor-associated inflammation.CK2 phosphorylates and inhibits TAp73 tumor suppressor function to promote expression of cancer stem cell genes and phenotype in head and neck cancer.Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer.Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma.Mutations in RIPK4 cause the autosomal-recessive form of popliteal pterygium syndrome.The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells.Polo-like kinase 2 acting as a promoter in human tumor cells with an abundance of TAp73.ΔNp63α represses anti-proliferative genes via H2A.Z deposition.Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma.Anti-apoptotic brain and reproductive organ-expressed proteins enhance cisplatin resistance in lung cancer cells via the protein kinase B signaling pathway.Gastro-duodenal fluid induced nuclear factor-κappaB activation and early pre-malignant alterations in murine hypopharyngeal mucosa PI3K/mTOR inhibitor PF-04691502 antitumor activity is enhanced with induction of wild-type TP53 in human xenograft and murine knockout models of head and neck cancer.HSP90 Inhibitor SNX5422/2112 Targets the Dysregulated Signal and Transcription Factor Network and Malignant Phenotype of Head and Neck Squamous Cell Carcinoma.TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer.The diverse and complex roles of NF-κB subunits in cancer.Crosstalk among p53 family members in cutaneous carcinoma.Emerging from the shade of p53 mutants: N-terminally truncated variants of the p53 family in EMT signaling and cancer progression.Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding.High-depth, high-accuracy microsatellite genotyping enables precision lung cancer risk classification.In vitro model for gastroduodenal reflux-induced nuclear factor-kappaB activation and its role in hypopharyngeal carcinogenesis.c-Rel is a critical mediator of NF-κB-dependent TRAIL resistance of pancreatic cancer cells.Integration of high-risk human papillomavirus into cellular cancer-related genes in head and neck cancer cell lines.Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63.ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis.miR-21, miR-155, miR-192, and miR-375 Deregulations Related to NF-kappaB Activation in Gastroduodenal Fluid-Induced Early Preneoplastic Lesions of Laryngeal Mucosa In Vivo.Inhibition of NF-κB prevents the acidic bile-induced oncogenic mRNA phenotype, in human hypopharyngeal cells.Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

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TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer

http://www.wikidata.org/entity/Q35501271

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年論文

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TNF-α promotes c-REL/ΔNp63α in ...... ptosis in head and neck cancer

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Bin Yan

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Carter Van Waes

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Clint T Allen

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Hai Lu

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Jonah Cohen

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Kathryn E King

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Liesl Nottingham

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Satrajit Sinha

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P2860

p63 is a prostate basal cell marker and is required for prostate development

Selection of optimal kappa B/Rel DNA-binding motifs: interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation

WAF1, a potential mediator of p53 tumor suppression

The c-Rel transcription factor and B-cell proliferation: a deal with the devil

Activation of multiple NF-kappa B/Rel DNA-binding complexes by tumor necrosis factor

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

TP53 mutations and survival in squamous-cell carcinoma of the head and neck.

Clinical outcomes and correlates of TP53 mutations and cancer.

Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha.

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6867-6877

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21

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21933882

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3206154

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