IFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomas
about
The urgent need to recover MHC class I in cancers for effective immunotherapyCombination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine.CD8 engineered cytotoxic T cells reprogram melanoma tumor environment.Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune PathwaysAutophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors.Distinct patterns of cytolytic T-cell activation by different tumour cells revealed by Ca2+ signalling and granule mobilization.Immunoplasticity in cutaneous melanoma: beyond pure morphology.Immune surveillance in melanoma: From immune attack to melanoma escape and even counterattack.Transcriptome analysis of human colorectal cancer biopsies reveals extensive expression correlations among genes related to cell proliferation, lipid metabolism, immune response and collagen catabolism.Control of CD8 T cell proliferation and terminal differentiation by active STAT5 and CDKN2A/CDKN2B.
P2860
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P2860
IFNγ producing CD8(+) T cells modified to resist major immune checkpoints induce regression of MHC class I-deficient melanomas
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@ast
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@en
type
label
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@ast
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@en
prefLabel
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@ast
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@en
P2093
P2860
P1433
P1476
IFNγ producing CD8(+) T cells ...... HC class I-deficient melanomas
@en
P2093
Amandine Mas
Fanny Arnoux
Lee Leserman
Lionel Chasson
Magali Grange
Michel Buferne
Mélanie Bertuzzi
Philippe Naquet
P2860
P304
P356
10.4161/2162402X.2014.974959
P577
2015-02-01T00:00:00Z