Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice. - Wikidata - wikimedia - TriplyDB

Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.

Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.

http://www.wikidata.org/entity/Q35525708

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The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease Current data on IL-17 and Th17 cells and implications for graft versus host disease.Endothelial microparticles delivering microRNA-155 into T lymphocytes are involved in the initiation of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation.α-1-Antitrypsin (AAT)-modified donor cells suppress GVHD but enhance the GVL effect: a role for mitochondrial bioenergetics.T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.T-bet is critical for the development of acute graft-versus-host disease through controlling T cell differentiation and function CD4+ T cell STAT3 phosphorylation precedes acute GVHD, and subsequent Th17 tissue invasion correlates with GVHD severity and therapeutic response.The Free Radical Scavenger NecroX-7 Attenuates Acute Graft-versus-Host Disease via Reciprocal Regulation of Th1/Regulatory T Cells and Inhibition of HMGB1 Release.Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice.Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt.Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms T-bet Promotes Acute Graft-versus-Host Disease by Regulating Recipient Hematopoietic Cells in Mice.Essentials of Th17 cell commitment and plasticity Ion channels in innate and adaptive immunity Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease.PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD CD8(+) Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4(+) Tregs in mice The Nlrp3 inflammasome regulates acute graft-versus-host disease.Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice.c-Rel in GVHD biology: a missing link.STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity.c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice.HIF-1α inhibitor echinomycin reduces acute graft-versus-host disease and preserves graft-versus-leukemia effect The IL-17 differentiation pathway and its role in transplant outcome.The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation.Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice.Haploidentical SCT: the mechanisms underlying the crossing of HLA barriers.Inhibition of the interleukin-6 signaling pathway: a strategy to induce immune tolerance.Helper T-cell differentiation in graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.Altered homeostatic regulation of innate and adaptive immunity in lower gastrointestinal tract GVHD pathogenesis.Tbet is a critical modulator of FoxP3 expression in autoimmune graft-versus-host disease Regulatory B cells promote graft-versus-host disease prevention and maintain graft-versus-leukemia activity following allogeneic bone marrow transplantation.Chronic graft-versus-host disease: biological insights from preclinical and clinical studies.Cutaneous Graft-Versus-Host Disease: Diagnosis and Treatment.PD-L1 interacts with CD80 to regulate graft-versus-leukemia activity of donor CD8+ T cells.Increased plasmacytoid dendritic cells and RORγt-expressing immune effectors in cutaneous acute graft-versus-host disease.

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Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.

http://www.wikidata.org/entity/Q35525708

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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type

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

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Prevention of GVHD while spari ...... actor T-bet and RORγt in mice.

@en

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Chen Liu

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Claudio Anasetti

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Dapeng Wang

http://www.w3.org/2001/XMLSchema#string

Kane Kaosaard

http://www.w3.org/2001/XMLSchema#string

Kenrick Semple

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Xue-Zhong Yu

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Yu Yu

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P2860

A novel transcription factor, T-bet, directs Th1 lineage commitment

MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis

Leukocyte migration and graft-versus-host disease.

Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia.

The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation.

Th2 and Tc2 cells in the regulation of GVHD, GVL, and graft rejection: considerations for the allogeneic transplantation therapy of leukemia and lymphoma.

Regulatory T cells in transplantation tolerance.

Cytokine dysregulation and acute graft-versus-host disease.

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5011-5020

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18

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