Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A
about
Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused reviewSignaling effectors underlying pathologic growth and remodeling of the heartp21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsThe Role of ERK1/2 in the Development of Diabetic CardiomyopathyPAK1 is a novel cardiac protective signaling moleculeSmall and large animal models in cardiac contraction research: advantages and disadvantagesTNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide.P21-activated kinase in inflammatory and cardiovascular disease.Metabolic efficiency promotes protection from pressure overload in hearts expressing slow skeletal troponin I.Mechanical stress triggers cardiomyocyte autophagy through angiotensin II type 1 receptor-mediated p38MAP kinase independently of angiotensin II.Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor.p21-activated kinase improves cardiac contractility during ischemia-reperfusion concomitant with changes in troponin-T and myosin light chain 2 phosphorylationAMP-activated protein kinase phosphorylates cardiac troponin I at Ser-150 to increase myofilament calcium sensitivity and blunt PKA-dependent function.Knockout of p21-activated kinase-1 attenuates exercise-induced cardiac remodelling through altered calcineurin signallingNovel roles of PAK1 in the heart.Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heartAngiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signalingMyofilament Calcium Sensitivity: Mechanistic Insight into TnI Ser-23/24 and Ser-150 Phosphorylation Integration.p21-Activated kinase1 (Pak1) is a negative regulator of NADPH-oxidase 2 in ventricular myocytes.Impact of dietary selenium intake on cardiac health: experimental approaches and human studies.p21-Activated protein kinases and their emerging roles in glucose homeostasis.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Structure, biochemistry, and biology of PAK kinases.miR-30c Mediates Upregulation of Cdc42 and Pak1 in Diabetic Cardiomyopathy.The p21-activated kinase 1 (Pak1) signalling pathway in cardiac disease: from mechanistic study to therapeutic exploration.Mouse models for the study of postnatal cardiac hypertrophy.PAK4-6 in cancer and neuronal development.MK5: A novel regulator of cardiac fibroblast function?
P2860
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P2860
Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@ast
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@en
type
label
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@ast
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@en
prefLabel
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@ast
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@en
P2093
P2860
P1476
Ablation of p21-activated kina ...... tion of protein phosphatase 2A
@en
P2093
Beata M Wolska
Domenico M Taglieri
Ivana Knezevic
Katherine A Sheehan
Michelle M Monasky
R John Solaro
P2860
P304
P356
10.1016/J.YJMCC.2011.09.016
P577
2011-09-24T00:00:00Z