A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.

A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.

Item
http://www.wikidata.org/entity/Q35538543
New Horizons in Diabetic Neuropathy: Mechanisms, Bioenergetics, and Pain.Oral administration of PF-01247324, a subtype-selective Nav1.8 blocker, reverses cerebellar deficits in a mouse model of multiple sclerosisInhibition of Late Sodium Current as an Innovative Antiarrhythmic Strategy.Control of Neurotransmission by NaV1.7 in Human, Guinea Pig, and Mouse Airway Parasympathetic Nerves.Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.Inflammatory Pain Reduces C Fiber Activity-Dependent Slowing in a Sex-Dependent Manner, Amplifying Nociceptive Input to the Spinal Cord.Discovery and Optimization of Selective Nav1.8 Modulator Series That Demonstrate Efficacy in Preclinical Models of Pain.Morphological and functional diversity of first-order somatosensory neurons.The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels.Sodium channels in pain disorders: pathophysiology and prospects for treatment.Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.Different role of tetrodotoxin-sensitive voltage-gated sodium channel (NaV1) subtypes in action potential initiation and conduction in vagal airway nociceptors.A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line.Ionic Mechanism Underlying Rebound Depolarization in Medial Prefrontal Cortex Pyramidal Neurons.
P2860

A novel selective and orally bioavailable Nav 1.8 channel blocker, PF-01247324, attenuates nociception and sensory neuron excitability.

Item
http://www.wikidata.org/entity/Q35538543
description
2015 nî lūn-bûn
@nan
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A novel selective and orally b ...... d sensory neuron excitability.
@ast
A novel selective and orally b ...... d sensory neuron excitability.
@en
type
label
A novel selective and orally b ...... d sensory neuron excitability.
@ast
A novel selective and orally b ...... d sensory neuron excitability.
@en
prefLabel
A novel selective and orally b ...... d sensory neuron excitability.
@ast
A novel selective and orally b ...... d sensory neuron excitability.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
A novel selective and orally b ...... d sensory neuron excitability.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932