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Overlap and effective size of the human CD8+ T cell receptor repertoire

Overlap and effective size of the human CD8+ T cell receptor repertoire

http://www.wikidata.org/entity/Q35539339

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On the organization of human T-cell receptor loci: log-periodic distribution of T-cell receptor gene segments Donor Unrestricted T Cells: A Shared Human T Cell Response Narrowing the Gap: Preserving Repertoire Diversity Despite Clonal Selection during the CD4 T Cell Response Biomarkers for glioma immunotherapy: the next generation Human memory T cells: generation, compartmentalization and homeostasis Applications of next-generation sequencing to blood and marrow transplantation Indoctrinating T cells to attack pathogens through homeschooling Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells Next generation sequencing: new tools in immunology and hematology Emerging concepts in tissue-resident T cells: lessons from humans αβ T cell receptors as predictors of health and disease T cells and their eons-old obsession with MHC Palindromic nucleotide analysis in human T cell receptor rearrangements Integrative network modeling approaches to personalized cancer medicine A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status T-cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death-ligand 1 expression in patients with soft tissue sarcomas.Exhaustive T-cell repertoire sequencing of human peripheral blood samples reveals signatures of antigen selection and a directly measured repertoire size of at least 1 million clonotypes.Unbiased analysis of TCRα/β chains at the single-cell level in human CD8+ T-cell subsets Estimating the diversity, completeness, and cross-reactivity of the T cell repertoire.Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization MHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection.Membrane association of the CD3ε signaling domain is required for optimal T cell development and function.Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells.Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral Antigens Highly functional T-cell receptor repertoires are abundant in stem memory T cells and highly shared among individuals.Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire.Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires Quantifying selection in immune receptor repertoires.High-resolution description of antibody heavy-chain repertoires in humans.Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains.Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.Revisiting thymic positive selection and the mature T cell repertoire for antigen.Deep sequencing of the human TCRγ and TCRβ repertoires suggests that TCRβ rearranges after αβ and γδ T cell commitment Next generation sequencing for TCR repertoire profiling: platform-specific features and correction algorithms.T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity.Diversity-oriented approaches for interrogating T-cell receptor repertoire, ligand recognition, and function CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing.Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas.Diversity and clonal selection in the human T-cell repertoire.Engineering improved T cell receptors using an alanine-scan guided T cell display selection system

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Overlap and effective size of the human CD8+ T cell receptor repertoire

http://www.wikidata.org/entity/Q35539339

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2010 nî lūn-bûn

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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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SCITRANSLMED.3001442

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Science Translational Medicine

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Overlap and effective size of the human CD8+ T cell receptor repertoire

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P2093

Cameron J Turtle

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Christopher S Carlson

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Edus H Warren

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Harlan S Robins

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Jessica Andriesen

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Paulo V Campregher

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Santosh K Srivastava

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Stanley R Riddell

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P2860

How TCRs bind MHCs, peptides, and coreceptors

T-cell antigen receptor genes and T-cell recognition

High-throughput sequencing of the zebrafish antibody repertoire.

Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets.

Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements.

Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus.

Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferase

The molecular basis for public T-cell responses?

Comprehensive assessment of T-cell receptor beta-chain diversity in alphabeta T cells.

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47

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20811043

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3212437

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