Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
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Review: Multiple system atrophy: emerging targets for interventional therapiesNeuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein AggregationImmunotherapy in Parkinson's Disease: Micromanaging Alpha-Synuclein AggregationAuditory- and Vestibular-Evoked Potentials Correlate with Motor and Non-Motor Features of Parkinson's Disease.Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy.Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington's diseaseImmunomodulation as a neuroprotective and therapeutic strategy for Parkinson's disease.Immunotherapeutic Approaches Targeting Amyloid-β, α-Synuclein, and Tau for the Treatment of Neurodegenerative Disorders.Combination therapies: The next logical Step for the treatment of synucleinopathies?Review: Novel treatment strategies targeting alpha-synuclein in multiple system atrophy as a model of synucleinopathyα-Synuclein-induced myelination deficit defines a novel interventional target for multiple system atrophy.Combination of alpha-synuclein immunotherapy with anti-inflammatory treatment in a transgenic mouse model of multiple system atrophyAnti-α-synuclein immunotherapy reduces α-synuclein propagation in the axon and degeneration in a combined viral vector and transgenic model of synucleinopathy.Active immunization therapies for Parkinson's disease and multiple system atrophy.Development of Passive Immunotherapies for Synucleinopathies.Toward disease modification in multiple system atrophy: Pitfalls, bottlenecks, and possible remedies.Immunotherapies for neurodegenerative diseases: current status and potential of plant-made biopharmaceuticals.Multiple System Atrophy - State of the Art.The PROMESA-protocol: progression rate of multiple system atrophy under EGCG supplementation as anti-aggregation-approach.Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles.A novel panel of α-synuclein antibodies reveal distinctive staining profiles in synucleinopathies.α-synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease.MultiTEP platform-based DNA vaccines for alpha-synucleinopathies: preclinical evaluation of immunogenicity and therapeutic potency.The neuropathology of multiple system atrophy and its therapeutic implications.Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy.Multiple system atrophy: experimental models and reality.Identification and characterization of antibodies elicited by human cystatin C fragment.Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies.Vaccination strategies in tauopathies and synucleinopathies.Multiple System Atrophy: An Oligodendroglioneural Synucleinopathy.Region-Specific Effects of Immunotherapy With Antibodies Targeting α-synuclein in a Transgenic Model of Synucleinopathy.Microglia Response During Parkinson's Disease: Alpha-Synuclein InterventionModel Senescent Microglia Induce Disease Related Changes in α-Synuclein Expression and Activity
P2860
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P2860
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Active immunization against al ...... del of multiple system atrophy
@ast
Active immunization against al ...... del of multiple system atrophy
@en
type
label
Active immunization against al ...... del of multiple system atrophy
@ast
Active immunization against al ...... del of multiple system atrophy
@en
prefLabel
Active immunization against al ...... del of multiple system atrophy
@ast
Active immunization against al ...... del of multiple system atrophy
@en
P2093
P2860
P1476
Active immunization against al ...... del of multiple system atrophy
@en
P2093
Achim Schneeberger
Anthony Adame
Christina Patrick
Elvira Valera
Frank Mattner
Harald Weninger
Markus Mandler
Michael Mante
Radmila Santic
Sabine Schmidhuber
P2860
P2888
P356
10.1186/S13024-015-0008-9
P577
2015-03-19T00:00:00Z
P5875
P6179
1039092100