Photoaffinity labeling in target- and binding-site identification
about
Chemical proteomics approaches for identifying the cellular targets of natural productsPhoto-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs).Novel Azido-Iodo Photoaffinity Ligands for the Human Serotonin Transporter Based on the Selective Serotonin Reuptake Inhibitor (S)-Citalopram.Target identification for biologically active small molecules using chemical biology approaches.Identification of protein binding partners of small molecules using label-free methods.Development of Photoactivatable Allosteric Modulators for the Chemokine Receptor CXCR3.Recent developments and applications of clickable photoprobes in medicinal chemistry and chemical biology.Chalcone: A Privileged Structure in Medicinal Chemistry.Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase.Synthesis of Arylazide- and Diazirine-Containing CrAsH-EDT2 Photoaffinity Probes.Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids.Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes.Identification of peptide-binding sites within BSA using rapid, laser-induced covalent cross-linking combined with high-performance mass spectrometry.Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6.Discovery of stimulator binding to a conserved pocket in the heme domain of soluble guanylyl cyclase.Direct and indirect approaches to identify drug modes of action.Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences.Unambiguous Identification of β-Tubulin as the Direct Cellular Target Responsible for the Cytotoxicity of Chalcone by Photoaffinity Labeling.Characterisation of Photoaffinity-Based Chemical Probes by Fluorescence Imaging and Native-State Mass Spectrometry.Elucidation of inhibitor-binding pockets of d-amino acid oxidase using docking simulation and N-sulfanylethylanilide-based labeling technology.A Whole Proteome Inventory of Background Photocrosslinker Binding.Synthesis and characterization of photoaffinity labelling reagents towards the Hsp90 C-terminal domain.Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling.Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog.Importance of a 4-Alkyl Substituent for Activity in the Englerin Series.Insights into the development of chemical probes for RNA
P2860
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P2860
Photoaffinity labeling in target- and binding-site identification
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Photoaffinity labeling in target- and binding-site identification
@ast
Photoaffinity labeling in target- and binding-site identification
@en
type
label
Photoaffinity labeling in target- and binding-site identification
@ast
Photoaffinity labeling in target- and binding-site identification
@en
prefLabel
Photoaffinity labeling in target- and binding-site identification
@ast
Photoaffinity labeling in target- and binding-site identification
@en
P2860
P356
P1476
Photoaffinity labeling in target- and binding-site identification
@en
P2093
Ewan Smith
Ian Collins
P2860
P304
P356
10.4155/FMC.14.152
P577
2015-02-01T00:00:00Z